KHDRBS2 抗体 (C-Term)
-
- 抗原 See all KHDRBS2 抗体
- KHDRBS2 (KH Domain Containing, RNA Binding, Signal Transduction Associated 2 (KHDRBS2))
-
抗原表位
- C-Term
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This KHDRBS2 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- TAPSRGRGGA IPPPPPPGRG VLTPRGSTVT RGALPVPPVA RGVPTPRARG APTVPGYRAP PPPAHEAYEE YGYDDGYGGE YDDQTYETYD NSYATQTQSV PEYYDYGHGV SEDAYDSYAP EEWATTRSSL KAPPQRSARG GYREHPYGRY
- 交叉反应
- 人, 小鼠
- 产品特性
- Polyclonal Antibodies
- 免疫原
- A synthetic peptide corresponding to a sequence within amino acids 200 to the C-terminus of human KHDRBS2 (NP_689901.2).
- 亚型
- IgG
- Top Product
- Discover our top product KHDRBS2 Primary Antibody
-
-
- 应用备注
- WB,1:500 - 1:1000,IHC,1:100 - 1:200
- 说明
-
HIGH QUALITY
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
- 抗原
- KHDRBS2 (KH Domain Containing, RNA Binding, Signal Transduction Associated 2 (KHDRBS2))
- 别名
- KHDRBS2 (KHDRBS2 产品)
- 别名
- slm1 antibody, slm-1 antibody, MGC145973 antibody, ba535f17.1 antibody, zgc:153588 antibody, SLM-1 antibody, SLM1 antibody, bA535F17.1 antibody, 6330586C16Rik antibody, Slim1 antibody, Slm1 antibody, KH RNA binding domain containing, signal transduction associated 2 antibody, KH domain containing, RNA binding, signal transduction associated 2 antibody, KHDRBS2 antibody, khdrbs2 antibody, Khdrbs2 antibody
- 背景
- RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. Binds both poly(A and poly(U homopolymers. Phosphorylation by PTK6 inhibits its RNA-binding ability (By similarity. Induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. Can regulate alternative splicing of NRXN1 in the laminin G-like domain 6 containing the evolutionary conserved neurexin alternative spliced segment 4 (AS4 involved in neurexin selective targeting to postsynaptic partners. Regulates cell-type specific alternative splicing of NRXN1 at AS4 and acts synergystically with SAM68 in exon skipping. In contrast acts antagonistically with SAM68 in NRXN3 exon skipping at AS4. Its phosphorylation by FYN inhibits its ability to regulate splice site selection. May function as an adapter protein for Src kinases during mitosis.,KHDRBS2,SLM-1,SLM1,Epigenetics & Nuclear Signaling,KHDRBS2
- 分子量
- 38 kDa
- 基因ID
- 202559
- UniProt
- Q5VWX1
-