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HFE2 抗体 (AA 1-174)

HFE2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6141738
发货至: 中国
  • 抗原 See all HFE2 抗体
    HFE2 (Hemochromatosis Type 2 (Juvenile) (HFE2))
    抗原表位
    • 15
    • 10
    • 8
    • 8
    • 7
    • 7
    • 6
    • 6
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-174
    适用
    • 79
    • 23
    • 10
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 71
    • 10
    克隆类型
    • 74
    • 7
    多克隆
    标记
    • 35
    • 9
    • 7
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This HFE2 antibody is un-conjugated
    应用范围
    • 74
    • 30
    • 27
    • 15
    • 13
    • 13
    • 9
    • 8
    • 8
    • 3
    • 3
    • 1
    Western Blotting (WB)
    序列
    MQECIDQKVY QAEVDNLPVA FEDGSINGGD RPGGSSLSIQ TANPGNHVEI QAAYIGTTII IRQTAGQLSF SIKVAEDVAM AFSAEQDLQL CVGGCPPSQR LSRSERNRRG AITIDTARRL CKEGLPVEDA YFHSCVFDVL ISGDPNFTVA AQAALEDARA FLPDLEKLHL FPSD
    交叉反应
    小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-174 of human HFE2 (NP_998817.1).
    亚型
    IgG
    Top Product
    Discover our top product HFE2 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000
    说明

    HIGH QUALITY

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    HFE2 (Hemochromatosis Type 2 (Juvenile) (HFE2))
    别名
    HFE2 (HFE2 产品)
    别名
    HFE2A antibody, HJV antibody, JH antibody, RGMC antibody, HFE2 antibody, DKFZp468F2322 antibody, 2310035L15Rik antibody, 5230400G09Rik antibody, AI414844 antibody, AI789733 antibody, DL-M antibody, Rgmc antibody, hemojuvelin antibody, RGMr antibody, hjv antibody, id:ibd3464 antibody, wu:fb38f10 antibody, zgc:136698 antibody, hemochromatosis type 2 (juvenile) antibody, hemochromatosis type 2 antibody, HFE2 antibody, Hfe2 antibody, hfe2 antibody
    背景
    The product of this gene is involved in iron metabolism. It may be a component of the signaling pathway which activates hepcidin or it may act as a modulator of hepcidin expression. It could also represent the cellular receptor for hepcidin. Two uORFs in the 5' UTR negatively regulate the expression and activity of the encoded protein. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. Defects in this gene are the cause of hemochromatosis type 2A, also called juvenile hemochromatosis (JH). JH is an early-onset autosomal recessive disorder due to severe iron overload resulting in hypogonadotrophic hypogonadism, hepatic fibrosis or cirrhosis and cardiomyopathy, occurring typically before age of 30.,HFE2,HFE2A,HJV,JH,RGMC,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Endocrine & Metabolism,Neuroscience,Neurodegenerative Diseases Markers,Other Neurological disorders,Stem Cells,Amyotrophic lateral sclerosis-ALS,HFE2
    分子量
    21 kDa/33 kDa/45 kDa
    基因ID
    148738
    UniProt
    Q6ZVN8
    途径
    Transition Metal Ion Homeostasis
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