FGFR4 抗体 (AA 22-150)
Quick Overview for FGFR4 抗体 (AA 22-150) (ABIN6140618)
抗原
See all FGFR4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 22-150
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序列
- LEASEEVELE PCLAPSLEQQ EQELTVALGQ PVRLCCGRAE RGGHWYKEGS RLAPAGRVRG WRGRLEIASF LPEDAGRYLC LARGSMIVLQ NLTLITGDSL TSSNDDEDPK SHRDPSNRHS YPQQAPYWT
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 22-150 of human FGFR4 (NP_998812.1).
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亚型
- IgG
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anti-Fibroblast Growth Factor Receptor 4 (FGFR4) (AA 22-369) antibody
FGFR4 适用: 人, 猴 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 8A1G2 unconjugated
anti-Fibroblast Growth Factor Receptor 4 (FGFR4) (AA 22-369) antibodyFGFR4 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 3B5B8 unconjugated
anti-Fibroblast Growth Factor Receptor 4 (FGFR4) (AA 24-55), (N-Term) antibodyFGFR4 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB38171 unconjugated
anti-Fibroblast Growth Factor Receptor 4 (FGFR4) (AA 24-55) antibodyFGFR4 适用: 人 WB, ELISA, IHC, FACS, IF 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor 4 (FGFR4) (AA 31-145) antibodyFGFR4 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 1E2 unconjugated
anti-Fibroblast Growth Factor Receptor 4 (FGFR4) antibodyFGFR4 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Fibroblast Growth Factor Receptor 4 (FGFR4) antibodyFGFR4 适用: 人 ELISA, IHC 宿主: 小鼠 Monoclonal 4H2B10B2 unconjugated
anti-Fibroblast Growth Factor Receptor 4 (FGFR4) (AA 1-100) antibodyFGFR4 适用: 人, 大鼠 ELISA, IHC (p), IF (p), IF (cc), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor 4 (FGFR4) (AA 168-369) antibodyFGFR4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor 4 (FGFR4) (AA 25-182) antibodyFGFR4 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- FGFR4 (Fibroblast Growth Factor Receptor 4 (FGFR4))
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别名
- FGFR4
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背景
- The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. The genomic organization of this gene, compared to members 1-3, encompasses 18 exons rather than 19 or 20. Although alternative splicing has been observed, there is no evidence that the C-terminal half of the IgIII domain of this protein varies between three alternate forms, as indicated for members 1-3. This particular family member preferentially binds acidic fibroblast growth factor and, although its specific function is unknown, it is overexpressed in gynecological tumor samples, suggesting a role in breast and ovarian tumorigenesis.,FGFR4,CD334,JTK2,TKF,Cancer,Signal Transduction,Kinase,Tyrosine kinases,Cell Biology & Developmental Biology,Growth factor,ESC Pluripotency and Differentiation,Immunology & Inflammation,CD markers,Neuroscience,Cell Type Marker,Stem Cells,Neural Stem Cells,Cardiovascular,Angiogenesis,Neural Stem Cell marker,FGFR4
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分子量
- 64 kDa/83 kDa/87 kDa
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基因ID
- 2264
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UniProt
- P22455
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding
抗原
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