DDR2 抗体 (AA 290-400)
Quick Overview for DDR2 抗体 (AA 290-400) (ABIN6139473)
抗原
See all DDR2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 290-400
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序列
- NMFAKGVKIF KEVQCYFRSE ASEWEPNAIS FPLVLDDVNP SARFVTVPLH HRMASAIKCQ YHFADTWMMF SEITFQSDAA MYNNSEALPT SPMAPTTYDP MLKVDDSNTR I
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 290-400 of human DDR2 (NP_001014796.1).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000
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说明
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HIGH QUALITY
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- DDR2 (Discoidin Domain Receptor tyrosine Kinase 2 (DDR2))
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别名
- DDR2
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背景
- Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation, and metabolism. In several cases the biochemical mechanism by which RTKs transduce signals across the membrane has been shown to be ligand induced receptor oligomerization and subsequent intracellular phosphorylation. This autophosphorylation leads to phosphorylation of cytosolic targets as well as association with other molecules, which are involved in pleiotropic effects of signal transduction. RTKs have a tripartite structure with extracellular, transmembrane, and cytoplasmic regions. This gene encodes a member of a novel subclass of RTKs and contains a distinct extracellular region encompassing a factor VIII-like domain. Alternative splicing in the 5' UTR results in multiple transcript variants encoding the same protein.,DDR2,MIG20a,NTRKR3,TKT,TYRO10,Signal Transduction,Kinase,Tyrosine kinases,Immunology & Inflammation,CD markers,Neuroscience,Cardiovascular,Heart,Cardiogenesis,DDR2
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分子量
- 96 kDa
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基因ID
- 4921
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UniProt
- Q16832
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途径
- RTK signaling
抗原
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