PCNA 抗体
Quick Overview for PCNA 抗体 (ABIN6139020)
抗原
See all PCNA 抗体适用
宿主
克隆类型
标记
应用范围
-
-
交叉反应
- Green Monkey, 人, 小鼠, 大鼠
-
产品特性
- Monoclonal Antibodies
-
纯化方法
- Affinity purification
-
免疫原
- A synthesized peptide derived from human PCNA
-
亚型
- IgG
-
-
-
-
应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,IP,1:50 - 1:200
-
说明
-
HIGH QUALITY
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- PCNA (Proliferating Cell Nuclear Antigen (PCNA))
-
别名
- PCNA
-
背景
- The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq, Jul 2008],ATLD2,Cancer,Cell Biology & Developmental Biology,Cell Cycle,Epigenetics & Nuclear Signaling,ErbB-HER Signaling Pathway,Signal Transduction,Stem Cells,Tumor biomarkers,PCNA
-
分子量
- 29 kDa
-
基因ID
- 5111
-
UniProt
- P12004
-
途径
- Telomere Maintenance, DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Autophagy
抗原
-