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ATP1A (AA 551-850) 抗体

适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6216025
发货至: 中国
  • 抗原
    ATP1A
    抗原表位
    AA 551-850
    适用
    宿主
    • 1
    克隆类型
    • 1
    多克隆
    标记
    • 1
    非结合性
    应用范围
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    RVLGFCHLFL PDEQFPEGFQ FDTDDVNFPI DNLCFVGLIS MIDPPRAAVP DAVGKCRSAG IKVIMVTGDH PITAKAIAKG VGIISEGNET VEDIAARLNI PVSQVNPRDA KACVVHGSDL KDMTSEQLDD ILKYHTEIVF ARTSPQQKLI IVEGCQRQGA IVAVTGDGVN DSPALKKADI GVAMGIAGSD VSKQAADMIL LDDNFASIVT GVEEGRLIFD NLKKSIAYTL TSNIPEITPF LIFIIANIPL PLGTVTILCI DLGTDMVPAI SLAYEQAESD IMKRQPRNPK TDKLVNERLI
    交叉反应
    人, 小鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 551-850 of human Na+/K+-ATPase (NP_000692.2).
    亚型
    IgG
  • 应用备注
    WB,1:500 - 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • Wang, Niu, Liu, Yuan, Liu, Fu: "Exercise improves glucose uptake in murine myotubes through the AMPKα2-mediated induction of Sestrins." in: Biochimica et biophysica acta. Molecular basis of disease, Vol. 1864, Issue 10, pp. 3368-3377, (2018) (PubMed).

  • 抗原
    ATP1A
    背景
    The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 1 subunit. Multiple transcript variants encoding different isoforms have been found for this gene.,ATP1A1,ATPase Na+/K+ transporting subunit alpha 1,ATP1A,CMT2DD,HOMGSMR2,Signal Transduction,Endocrine & Metabolism,ATP1A
    分子量
    74 kDa/109 kDa/112 kDa/113 kDa
    基因ID
    476
    UniProt
    P05023
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