PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
Store at -20°C. Avoid freeze / thaw cycles.
Wang, Niu, Liu, Yuan, Liu, Fu: "Exercise improves glucose uptake in murine myotubes through the AMPKα2-mediated induction of Sestrins." in: Biochimica et biophysica acta. Molecular basis of disease, Vol. 1864, Issue 10, pp. 3368-3377, (2018) (PubMed).
抗原
ATP1A
背景
The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 1 subunit. Multiple transcript variants encoding different isoforms have been found for this gene.,ATP1A1,ATPase Na+/K+ transporting subunit alpha 1,ATP1A,CMT2DD,HOMGSMR2,Signal Transduction,Endocrine & Metabolism,ATP1A