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- 抗原 See all AFT7 抗体
- AFT7 (Activating Transcription Factor 7 (AFT7))
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抗原表位
- AA 1-117
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This AFT7 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- MGDDRPFVCN APGCGQRFTN EDHLAVHKHK HEMTLKFGPA RTDSVIIADQ TPTPTRFLKN CEEVGLFNEL ASSFEHEFKK AADEDEKKAR SRTVAKKLVV FRPRLFLLCF GIIFLIG
- 交叉反应
- 人
- 产品特性
- Polyclonal Antibodies
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-117 of human ATF7 (NP_001193611.1).
- 亚型
- IgG
- Top Product
- Discover our top product AFT7 Primary Antibody
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anti-Activating Transcription Factor 7 (AFT7) (AA 50-270) antibody
AFT7 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Activating Transcription Factor 7 (AFT7) (N-Term) antibodyAFT7 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Activating Transcription Factor 7 (AFT7) (AA 1-117) antibodyAFT7 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Activating Transcription Factor 7 (AFT7) (AA 68-96), (N-Term) antibodyAFT7 适用: 人 WB, IF, FACS 宿主: 兔 Polyclonal RB21430 unconjugated
anti-Activating Transcription Factor 7 (AFT7) (AA 68-96) antibodyAFT7 适用: 人 WB, ELISA, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Activating Transcription Factor 7 (AFT7) (C-Term) antibodyVerified AFT7 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Activating Transcription Factor 7 (AFT7) antibodyAFT7 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Activating Transcription Factor 7 (AFT7) (AA 1-483) antibodyAFT7 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Activating Transcription Factor 7 (AFT7) (C-Term) antibodyAFT7 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Activating Transcription Factor 7 (AFT7) (AA 397-446) antibodyAFT7 适用: 人, 小鼠, 大鼠, Cow, Pig, 犬, 马, 兔, 豚鼠, Bat, 猴, Hamster WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB,1:500 - 1:2000
- 说明
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HIGH QUALITY
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- AFT7 (Activating Transcription Factor 7 (AFT7))
- 别名
- ATF7 (AFT7 产品)
- 别名
- ATFA antibody, 1110012F10Rik antibody, 9430065F09Rik antibody, AI549878 antibody, C130020M04Rik antibody, ATF7 antibody, fa97a09 antibody, fc25b12 antibody, wu:fa97a09 antibody, wu:fc25b12 antibody, atfa antibody, activating transcription factor 7 antibody, activating transcription factor 7b antibody, ATF7 antibody, Atf7 antibody, atf7b antibody, atf7 antibody
- 背景
- Stress-responsive chromatin regulator that plays a role in various biological processes including innate immunological memory, adipocyte differentiation or telomerase regulation. In absence of stress, contributes to the formation of heterochromatin and heterochromatin-like structure by recruiting histone H3K9 tri- and di-methyltransferases thus silencing the transcription of target genes such as STAT1 in adipocytes, or genes involved in innate immunity in macrophages and adipocytes (By similarity. Stress induces ATF7 phosphorylation that disrupts interactions with histone methyltransferase and enhances the association with coactivators containing histone acetyltransferase and/or histone demethylase, leading to disruption of the heterochromatin-like structure and subsequently transcriptional activation (By similarity. In response to TNF-alpha, which is induced by various stresses, phosphorylated ATF7 and telomerase are released from telomeres leading to telomere shortening. Plays also a role in maintaining epithelial regenerative capacity and protecting against cell death during intestinal epithelial damage and repair (By similarity.,ATF7,ATFA,Epigenetics & Nuclear Signaling,Transcription Factors,ATF7
- 分子量
- 13 kDa/33 kDa/49 kDa/50 kDa/51 kDa/52 kDa
- 基因ID
- 11016
- UniProt
- P17544
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