AGR2 抗体 (AA 21-175)
Quick Overview for AGR2 抗体 (AA 21-175) (ABIN6136646)
抗原
See all AGR2 抗体适用
宿主
克隆类型
标记
应用范围
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    - 
                                            抗原表位
- AA 21-175
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                                            序列
- RDTTVKPGAK KDTKDSRPKL PQTLSRGWGD QLIWTQTYEE ALYKSKTSNK PLMIIHHLDE CPHSQALKKV FAENKEIQKL AEQFVLLNLV YETTDKHLSP DGQYVPRIMF VDPSLTVRAD ITGRYSNRLY AYEPADTALL LDNMKKALKL LKTEL
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                                            交叉反应
- 人, 小鼠, 大鼠
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                                            产品特性
- Polyclonal Antibodies
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                                            纯化方法
- Affinity purification
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                                            免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 21-175 of human AGR2 (NP_006399.1).
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                                            亚型
- IgG
 
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    - 
                                            应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
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                                            说明
- 
                        HIGH QUALITY 
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                                            限制
- 仅限研究用
 
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    - 
                                            状态
- Liquid
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                                            缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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                                            储存液
- Sodium azide
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                                            注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            储存条件
- -20 °C
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                                            储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
 
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    - AGR2 (Anterior Gradient Homolog 2 (Xenopus Laevis) (AGR2))
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                                            别名
- AGR2
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                                            背景
- This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, and a C-terminal ER-retention sequence. This protein plays a role in cell migration, cellular transformation and metastasis and is as a p53 inhibitor. As an ER-localized molecular chaperone, it plays a role in the folding, trafficking, and assembly of cysteine-rich transmembrane receptors and the cysteine-rich intestinal gylcoprotein mucin. This gene has been implicated in inflammatory bowel disease and cancer progression.,AGR2,AG-2,AG2,GOB-4,HAG-2,HEL-S-116,HPC8,PDIA17,XAG-2,Cancer,Tumor biomarkers,Cell Biology & Developmental Biology,Stem Cells,AGR2
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                                            分子量
- 19 kDa
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                                            基因ID
- 10551
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                                            UniProt
- O95994
 抗原
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