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JNK 抗体 (Thr183)
MAPK8
适用: 人, 小鼠, 大鼠, 小鸡
WB, ELISA, IF, IHC (p)
宿主: 兔
Polyclonal
unconjugated
JNK抗体详情
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抗原
See all JNK (MAPK8) 抗体
JNK (MAPK8)
(Mitogen-Activated Protein Kinase 8 (MAPK8))
抗原表位
All epitopes for JNK 抗体
Thr183
适用
All reactivities for JNK 抗体
人, 小鼠, 大鼠, 小鸡
宿主
All hosts for JNK 抗体
兔
克隆类型
All clonalities for JNK 抗体
多克隆
标记
All conjugates for JNK 抗体
This JNK antibody is un-conjugated
应用范围
All applications for JNK 抗体
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
特异性
MAPK8,JNK1,PRKM8,SAPK1,SAPK1C,Mitogen-activated protein kinase 8,MAP kinase 8,MAPK 8,JNK-46,Stress-activated protein kinase 1c,SAPK1c,Stress-activated protein kinase JNK1,c-Jun N-terminal kinase 1,MAPK9,JNK2,PRKM9,SAPK1A,Mi
纯化方法
Affinity purification
免疫原
Synthesized peptide derived from human JNK1/2/3 around the non-phosphorylation site of Thr183.
亚型
IgG
Top Product
Discover our top product MAPK8 Primary Antibody
Alternatives
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anti-Mitogen-Activated Protein Kinase 8 (MAPK8) (pThr183), (pTyr185) antibody
MAPK8
适用: 人, 小鼠, 大鼠, 犬, 兔
WB, ELISA, IHC (p), FACS, IF (cc), IF (p), ICC, IHC (fro)
宿主: 兔
Polyclonal
unconjugated
anti-Mitogen-Activated Protein Kinase 8 (MAPK8) (AA 201-300) antibody
MAPK8
适用: 人, 小鼠, 大鼠, 小鸡, 犬
WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro)
宿主: 兔
Polyclonal
unconjugated
anti-Mitogen-Activated Protein Kinase 8 (MAPK8) (AA 151-250) antibody
MAPK8
适用: 人, 小鼠, 大鼠, 小鸡, Pig
WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro)
宿主: 兔
Polyclonal
unconjugated
使用细节
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应用备注
WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:10000
限制
仅限研究用
贮存及处理
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状态
Liquid
浓度
1 mg/mL
缓冲液
PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
Store at -20°C. Avoid freeze / thaw cycles.
JNK目标详情
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抗原
JNK (MAPK8)
(Mitogen-Activated Protein Kinase 8 (MAPK8))
别名
JNK1/2/3 (MAPK8 产品 )
别名
JNK antibody, JNK-46 antibody, JNK1 antibody, JNK1A2 antibody, JNK21B1/2 antibody, PRKM8 antibody, SAPK1 antibody, SAPK1c antibody, AI849689 antibody, Prkm8 antibody, BSK antibody, BSK/DJNK antibody, Bsk antibody, CG5680 antibody, D-JNK antibody, D-junk antibody, DBSK/JNK antibody, DJNK antibody, DJNK/bsk antibody, Dmel\\CG5680 antibody, JNK/SAPK antibody, Jnk antibody, Junk antibody, SAPKa antibody, c-Jun antibody, dJNK antibody, jnk antibody, T10F20.15 antibody, jnk1 antibody, sapk1 antibody, mapk8 antibody, zgc:112379 antibody, JNKb antibody, mapk8b antibody, mitogen-activated protein kinase 8 antibody, Stress-activated protein kinase jnk-1 antibody, basket antibody, Protein kinase superfamily protein antibody, mitogen-activated protein kinase 8 L homeolog antibody, mitogen-activated protein kinase 8b antibody, mitogen-activated protein kinase 8B-like antibody, MAPK8 antibody, jnk-1 antibody, Mapk8 antibody, bsk antibody, ATMPK8 antibody, mapk8.L antibody, mapk8b antibody, LOC109094263 antibody
背景
C-Jun N-terminal kinases (JNKs) phosphorylate and augment transcriptional activity of c-Jun. JNKs originate from three genes that yield ten isoforms through alternative mRNA splicing, including JNK1α1,JNK1β1, JNK2α1, JNK2β1 and JNK3α1, which represent the p46 isoforms, and JNK1α2, JNK1β2, JNK2α2, JNK2β2 and JNK3β2, which represent the p54 isoforms. JNKs coordinate cell responses to stress and influence regulation of cell growth and ransformation. The human JNK1 (PRKM8, SAPK1, MAPK8) gene maps to chromosome 10q11.22 and shares 83 % amino acid identity with JNK2. JNK1 is necessary for normal activation and differentiation of CD4 helper T (TH) cells into TH1 and TH2 effector cells. Capsaicin activates JNK1 and p38 in Ras-transformed human breast epithelial cells. Nitrogen oxides (NOx) upregulate JNK1 in addition to c-Fos, c-Jun and other signaling kinases, including MEKK1 and p38.
分子量
48kDa
基因ID
5599, 5601, 5602
途径
MAPK Pathway , WNT signaling , TLR signaling , Fc-epsilon Receptor Signaling Pathway , Neurotrophin Signaling Pathway , Activation of Innate immune Response , Hepatitis C , Toll-Like Receptors Cascades , Signaling of Hepatocyte Growth Factor Receptor , S100 Proteins
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