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CMKLR1 抗体

CMKLR1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5959097
发货至: 中国
  • 抗原 See all CMKLR1 抗体
    CMKLR1 (Chemokine-Like Receptor 1 (CMKLR1))
    适用
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    人, 小鼠, 大鼠
    宿主
    • 69
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    克隆类型
    • 68
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    多克隆
    标记
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    This CMKLR1 antibody is un-conjugated
    应用范围
    • 61
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    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    CHEMERINR,Chemokine like receptor 1,Chemokine-like receptor 1,CHEMR23,CMKLR1,CML1,DEZ,G protein coupled receptor ChemR23,G protein coupled receptor DEZ,G-protein coupled receptor ChemR23,G-protein coupled receptor DEZ,Orphan G protein coupled receptor,Orphan G protein coupled receptor Dez,Resolvin E1 receptor,RVER1
    纯化方法
    Affinity purification
    免疫原
    Synthesized peptide derived from the Internal region of human ChemR23
    亚型
    IgG
    Top Product
    Discover our top product CMKLR1 Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:20000
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol,  pH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    CMKLR1 (Chemokine-Like Receptor 1 (CMKLR1))
    别名
    ChemR23 (CMKLR1 产品)
    别名
    CHEMERINR antibody, ChemR23 antibody, DEZ antibody, RVER1 antibody, Gpcr27 antibody, mcmklr1 antibody, si:ch211-240b21.3 antibody, CMLKR1 antibody, Cmklr-1 antibody, GPCR antibody, chemerin chemokine-like receptor 1 antibody, chemokine-like receptor 1 antibody, CMKLR1 antibody, Cmklr1 antibody, cmklr1 antibody
    背景
    Receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1. Interaction with RARRES2 induces activation of intracellular signaling molecules, such as SKY, MAPK1/3 (ERK1/2), MAPK14/P38MAPK and PI3K leading to multifunctional effects, like, reduction of immune responses, enhancing of adipogenesis and angionesis. Resolvin E1 down-regulates cytokine production in macrophages by reducing the activation of MAPK1/3 (ERK1/2) and NF-kappa-B. Positively regulates adipogenesis and adipocyte metabolism. Acts as a coreceptor for several SIV strains (SIVMAC316, SIVMAC239, SIVMACL7E-FR and SIVSM62A), as well as a primary HIV-1 strain (92UG024-2).
    分子量
    42kDa
    基因ID
    1240
    UniProt
    Q99788
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