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BCL2L1 抗体 (Thr47)

The 兔 多克隆 anti-BCL2L1 antibody (ABIN5959000) specifically detects BCL2L1 in WB, IF, ELISA 和 IHC (p). The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN5959000
发货至: 中国
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Quick Overview for BCL2L1 抗体 (Thr47) (ABIN5959000)

抗原

See all BCL2L1 抗体
BCL2L1 (BCL2-Like 1 (BCL2L1))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This BCL2L1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    Thr47

    特异性

    Apoptosis regulator Bcl X,Apoptosis regulator Bcl-X,Apoptosis regulator BclX,B cell lymphoma 2 like,B2CL1,Bcl 2 like 1 protein,Bcl X,Bcl xL,BCL XL/S,Bcl xS,Bcl-2-like protein 1,Bcl2 Like 1,Bcl2 related gene,Bcl2-L-1,BCL2L,Bcl2l1,BCLX,BclXL,BclXs,DKFZp781P2092,PPP1R52,Protein phosphatase 1 regulatory subunit 52

    纯化方法

    Affinity purification

    免疫原

    Synthesized peptide derived from human Bcl-x around the non-phosphorylation site of Thr47.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:5000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    BCL2L1 (BCL2-Like 1 (BCL2L1))

    别名

    BCL-x

    背景

    Bcl x is a member of the Bcl 2 family of proteins, which function as regulators of apoptosis. It may provide neuroprotection against ischemic brian injury. Bcl x has two isoforms, Bcl xl (long) a 241 amino acid protein and Bcl xs (short) a 178 amino acid protein lacking a 63 amino acid domain that is well conserved among members of the Bcl2 family. Isoform Bcl-X(L) anti-apoptotic activity is inhibited by association with SIVA isoform 1. Inhibits activation of caspases. Appears to regulate cell death by blocking the voltage-dependent anion channnel (VDAC) by binding to it and preventing the release of the caspase activator, cytochrome c, from the mitochondrial membrane. The Bcl-X(S) isoform promotes apoptosis.

    分子量

    26kDa

    基因ID

    598

    UniProt

    Q07817

    途径

    Apoptosis, Negative Regulation of intrinsic apoptotic Signaling
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