FLJ10128,KIAA1561,MGC141967,MGC141969,Nuclear membrane binding protein,NUCLING,UACA,UACA,Uveal autoantigen with coiled coil domains and ankyrin repeats,Uveal autoantigen with coiled-coil domains and ankyrin repeats
Regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis. Promotes apoptosis by regulating three pathways, apoptosome up-regulation, LGALS3/galectin-3 down-regulation and NF-kappa-B inactivation. Regulates the redistribution of APAF1 into the nucleus after proapoptotic stress. Down-regulates the expression of LGALS3 by inhibiting NFKB1 (By similarity).