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PKC zeta 抗体 (Thr560)

This 兔 多克隆 antibody specifically detects PKC zeta in WB, ELISA, IF 和 IHC (p). It exhibits reactivity toward 人, 小鼠, 大鼠 和 猴.It has been mentioned in 1 publication
产品编号 ABIN5957396
发货至: 中国
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Quick Overview for PKC zeta 抗体 (Thr560) (ABIN5957396)

抗原

See all PKC zeta (PRKCZ) 抗体
PKC zeta (PRKCZ) (Protein Kinase C, zeta (PRKCZ))

适用

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人, 小鼠, 大鼠, 猴

宿主

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克隆类型

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多克隆

标记

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This PKC zeta antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    Thr560

    特异性

    14-3-3-zetaisoform,AI098070,aPKCzeta,C80388,EC 2.7.11.13,KPCZ,nPKC zeta,nPKC-zeta,OTTHUMP00000001368,OTTHUMP00000044160,PKC 2,PKC ZETA,PKC2,Pkcz,PKCZETA,PKM-zeta,included,PRKCZ,Protein kinase C zeta,Protein kinase C zeta form,Protein kinase C zeta type,r14-3-3,R74924,zetaPKC

    纯化方法

    Affinity purification

    免疫原

    Synthesized peptide derived from human PKC zeta around the non-phosphorylation site of Thr560.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:5000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • Fan, Li, Zhang, Yang, Li, Zeng, Deng: "PKCζ in prostate cancer cells represses the recruitment and M2 polarization of macrophages in the prostate cancer microenvironment." in: Tumour biology, Vol. 39, Issue 6, pp. 1010428317701442, (2017) (PubMed).

  • 抗原

    PKC zeta (PRKCZ) (Protein Kinase C, zeta (PRKCZ))

    别名

    PKC zeta

    背景

    This is a calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. Phosphorylates 'Ser-311' of RELA subunit of NF-kappa-B.PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters. Subunit of a quaternary complex that plays a central role in epithelial cell polarization.

    分子量

    68kDa

    基因ID

    5590

    UniProt

    Q05513

    途径

    NF-kappaB Signaling, RTK signaling, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Membrane, Production of Molecular Mediator of Immune Response, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
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