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Neuregulin 1 抗体

This anti-Neuregulin 1 antibody is a 兔 多克隆 antibody detecting Neuregulin 1 in WB 和 ELISA. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN5957266
发货至: 中国

Quick Overview for Neuregulin 1 抗体 (ABIN5957266)

抗原

See all Neuregulin 1 (NRG1) 抗体
Neuregulin 1 (NRG1)

适用

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人, 大鼠, 小鼠

宿主

  • 129
  • 20

克隆类型

  • 128
  • 21
多克隆

标记

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This Neuregulin 1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 特异性

    Acetylcholine receptor-inducing activity,Acetylcholine receptor-inducing activity,CHICK,homolog of,ARIA,Breast cancer cell differentiation factor p45,GGF,GGF2,Glial growth factor,Heregulin,heregulin,alpha (45kD,ERBB2 p185-activator),HGL,HRG,HRG1,HRGA,MST131,NDF,Neu differentiation factor,Neuregulin 1,neuregulin 1 type IV beta 1a,neuregulin 1 type IV beta 3,Neuregulin-1,NRG 1,nrg1,NRG1-IT2,NRG1,OTTHUMP00000225398,OTTHUMP00000225419,OTTHUMP00000225420,OTTHUMP00000225421,OTTHUMP00000225422,OTTHUMP00000225477,OTTHUMP00000225545,OTTHUMP00000230603,OTTHUMP00000230605,pro-neuregulin-1,membrane-bound isoform,Pro-NRG1,ProNRG1,Sensory and motor neuron-derived factor,SMDF

    纯化方法

    Affinity purification

    免疫原

    Synthesized peptide derived from the N-terminal region of human Neuregulin-1.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, ELISA 1:20000

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide,0.5 % BSA and 50 % glycerol  pH 7.4.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    Neuregulin 1 (NRG1)

    别名

    Neuregulin-1

    背景

    The protein encoded by this gene was originally identified as a 44-kD glycoprotein that interacts with the NEU/ERBB2 receptor tyrosine kinase to increase its phosphorylation on tyrosine residues. This protein is a signaling protein that mediates cell-cell interactions and plays critical roles in the growth and development of multiple organ systems. It is known that an extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are tissue-specifically expressed and differ significantly in their structure, and thereby these isoforms are classified into types I, II, III, IV, V and VI. The gene dysregulation has been linked to diseases such as cancer, schizophrenia and bipolar disorder (BPD).

    分子量

    70kDa

    基因ID

    3084

    UniProt

    Q02297

    途径

    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation
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