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Caspase 10 B/C 抗体

适用: 人 ELISA, IF, WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5956727
发货至: 中国
  • 抗原
    Caspase 10 B/C
    适用
    宿主
    • 2
    克隆类型
    • 2
    多克隆
    标记
    • 2
    非结合性
    应用范围
    • 2
    • 2
    • 2
    • 1
    • 1
    ELISA, Immunofluorescence (IF), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    ALPS2,apoptotic protease Mch-4,CASP-10,CASPA,caspase-10,FADD-like ICE2,FAS-associated death domain protein interleukin-1B-convert
    纯化方法
    Affinity purification
    免疫原
    Synthesized peptide derived from the C-terminal region of human Caspase-10 B/C
    亚型
    IgG
  • 应用备注
    WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:10000
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol,  pH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    Caspase 10 B/C
    别名
    Caspase-10 B/C
    背景
    Involved in the activation cascade of caspases responsible for apoptosis execution. Recruited to both Fas- and TNFR-1 receptors in a FADD dependent manner. May participate in the granzyme B apoptotic pathways. Cleaves and activates caspase-3, -4, -6, -7, -8, and -9. Hydrolyzes the small- molecule substrates, Tyr-Val-Ala-Asp-AMC and Asp-Glu-Val-Asp-AMC.Isoform C is proteolytically inactive.
    分子量
    59kDa
    基因ID
    843
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