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- 抗原
- CASP4 p20
- 抗原表位
- Cleaved-Gln81
- 适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
-
标记
- 非结合性
- 应用范围
- ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
- 特异性
- Apoptotic cysteine protease Mih1/TX,CASP-4,CASP4,CASP4,Caspase 4 apoptosis related cysteine peptidase,Caspase-4 subunit 2,Caspase4,ICE(rel)-II,ICE(rel)II,ICEREL II,ICH2,Mih1/TX,Protease ICH-2,Protease TX,TX
- 纯化方法
- Affinity purification
- 免疫原
- Synthesized peptide derived from the Internal region of human Caspase-4 p20
- 亚型
- IgG
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anti-CASP4 p20 (Cleaved-Gln81) antibody
适用: 人 ELISA, IHC (p), WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- CASP4 p20
- 背景
- This gene encodes a member of the cysteine proteases that plays important roles in apoptosis, cell migration and the inflammatory response. The encoded protein mediates production of pro-inflammatory cytokines by macrophages upon bacterial infection. Mice lacking the encoded protein are resistant to endotoxic shock induced by lipopolysaccharide. A 5-bp deletion encompassing a splice acceptor junction resulting in alternate splicing and a shorter non-functional isoform in certain mouse strains has been described. Although its official nomenclature is "caspase 4, apoptosis-related cysteine peptidase", this gene and its encoded protein have historically been called caspase 11. This gene is present in a cluster of three caspase genes on chromosome 9.
- 分子量
- 43kDa
- 基因ID
- 837
- UniProt
- P49662
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