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NF-kB p65 抗体 (C-Term)

The 兔 多克隆 anti-NF-kB p65 antibody is suitable to detect NF-kB p65 in samples from 人, 小鼠 和 大鼠. It has been validated for WB, ELISA, IP 和 GS.
产品编号 ABIN576233
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for NF-kB p65 抗体 (C-Term) (ABIN576233)

抗原

See all NF-kB p65 (NFkBP65) 抗体
NF-kB p65 (NFkBP65) (Nuclear Factor-kB p65 (NFkBP65))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This NF-kB p65 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunoprecipitation (IP), Gel Shift (GS)
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    C-Term

    特异性

    Recognizes the human Transcription factor p65, also known as Nuclear factor NF-kappa-B p65 subunit, NFkappaB p65, RelA or Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3. NFkappaB p65 is a 551 amino acid ~65 kD subunit of the NFkappaB transcription factor present in most cell types and is involved as the endpoint in an array of signal transduction events related to many processes including apotosis, immunity, inflammation and tumorigenesis. The most abundant form of NFkappaB appears to be the p65-p50 heterodimer. In the active form NFkappaB p65 is found in the nucleus co-localizing with the ATP-dependent RNA helicase. NFkappaB p65 is also found in an inactive form in the cytoplasm associated with the inhibitor IkappaB In a gel supershift assaywas found to be active against all p65 containing human, mouse or rat NFkappaB complexes using 0.5 μL to 1.0 μL per assay. The binding ofto the NFkappaB p65 subunit can be blocked using the NFkappaB p65 control peptide.

    免疫原

    NFkB p65 peptide corresponding to the C-terminus region of the human protein conjugated to KLH.

    Type of Immunogen: Synthetic peptide

    亚型

    IgG
  • 应用备注

    Approved: ELISA (1:5000 - 1:25000), GS, IP, WB (1:2000 - 1:5000)

    说明

    Target Species of Antibody: Human

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Serum, 0.01 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • 抗原

    NF-kB p65 (NFkBP65) (Nuclear Factor-kB p65 (NFkBP65))

    别名

    RELA / NFKB p65

    背景

    Name/Gene ID: RELA

    Synonyms: RELA, NF-kappa-B p65delta3, NFKB3, p65, Transcription factor p65

    基因ID

    5970

    途径

    NF-kappaB Signaling, RTK signaling, TCR Signaling, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Toll-Like Receptors Cascades, S100 Proteins
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