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CD161 抗体 (APC)

KLRB1 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal HP-3G10 APC
产品编号 ABIN5711621
发货至: 中国
  • 抗原 See all CD161 (KLRB1) 抗体
    CD161 (KLRB1) (Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1))
    适用
    • 47
    • 15
    • 6
    • 2
    • 2
    • 2
    人, Non-Human Primate
    宿主
    • 43
    • 17
    小鼠
    克隆类型
    • 42
    • 18
    单克隆
    标记
    • 26
    • 10
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD161 antibody is conjugated to APC
    应用范围
    • 40
    • 24
    • 12
    • 10
    • 10
    • 8
    • 5
    • 4
    • 2
    • 1
    • 1
    Flow Cytometry (FACS)
    特异性
    The mouse monoclonal antibody HP-3G10 recognizes an extracellular epitope of CD161, a type II transmembrane C-type lectin receptor, expressed on the plasma membrane of NK cells, dendritic cells, activated monocytes and a subset of T cells as a disulphide-linked homodimer.
    交叉反应 (详细)
    Human, Non-Human Primates
    纯化方法
    Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
    免疫原
    human NK cells
    克隆位点
    HP-3G10
    亚型
    IgG1 kappa
    Top Product
    Discover our top product KLRB1 Primary Antibody
  • 应用备注
    Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
    说明

    The purified antibody is conjugated with cross-linked Allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.

    限制
    仅限研究用
  • 缓冲液
    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    The purified antibody is conjugated with cross-linked Allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • 抗原
    CD161 (KLRB1) (Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1))
    别名
    CD161 (KLRB1 产品)
    别名
    NKR-P1 antibody, KLRB1 antibody, 4930431A04Rik antibody, Gm4696 antibody, Klrb1g antibody, Klrb6 antibody, Ly-55 antibody, Ly55 antibody, NKR-P1G antibody, Nkrp-1e antibody, Nkrp1g antibody, CD161 antibody, CLEC5B antibody, NKR antibody, NKR-P1A antibody, NKRP1A antibody, hNKR-P1A antibody, Klrb1d antibody, Klrb1f antibody, Nkr-p1e antibody, killer cell lectin like receptor B1 antibody, killer cell lectin-like receptor subfamily B member 1 antibody, killer cell lectin-like receptor subfamily B, member 1 antibody, KLRB1 antibody, Klrb1 antibody
    背景
    Killer cell lectin like receptor B1,CD161, also known as Nkrp1 (natural killer receptor protein 1) or Klrb1 (killer cell lectin-like receptor subfamily b member 1), is a disulphide-linked homodimeric receptor, which is involved in regulation of NK cell and NKT cell function. It is expressed on rat NK cells, subset of T cells, dendritic cells, and activated monocytes. Although human CD161 is expressed as one isoform, the rat CD161 has three isoforms, referred to as CD161a, b, and c. These proteins contain C-terminal C-type lectin extracellular domain, a transmembrane domain, and N-terminal intracellular domain, which contains ITIM motif, such as CD161b, and displays inhibitory function, or does not contain ITIM motif, thus also not the inhibitory function, such as CD161a.,NKRP1A, KLRB1, CLEC5B
    基因ID
    3820
    UniProt
    Q12918
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