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- 抗原 See all KIR2DL5A 抗体
- KIR2DL5A (Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 5A (KIR2DL5A))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This KIR2DL5A antibody is conjugated to APC
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应用范围
- Flow Cytometry (FACS)
- 特异性
- The mouse monoclonal antibody UP-R1 recognizes an extracellular epitope on CD158f (KIR2DL5), a 60 kDa glycoprotein serving as a HLA class I ligand, and mainly expressed on a subset of NK cells and a small population of T cells. Its expression is highly polymorphic between individuals.
- 交叉反应 （详细）
- Human
- 纯化方法
- Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
- 免疫原
- Human CD158f-Ig fusion protein
- 克隆位点
- UP-R1
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product KIR2DL5A Primary Antibody
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anti-Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 5A (KIR2DL5A) antibody
KIR2DL5A 适用: 人 FACS, ICC 宿主: 小鼠 Monoclonal UP-R1 unconjugated
anti-Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 5A (KIR2DL5A) (AA 31-80) antibodyKIR2DL5A 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 5A (KIR2DL5A) antibodyKIR2DL5A 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 5A (KIR2DL5A) antibody (PE)KIR2DL5A 适用: 人 FACS 宿主: 小鼠 Monoclonal UP-R1 PE
anti-Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 5A (KIR2DL5A) (AA 121-170) antibodyKIR2DL5A 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 5A (KIR2DL5A) (AA 1-375) antibodyKIR2DL5A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 5A (KIR2DL5A) (AA 1-375) antibodyKIR2DL5A 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 5A (KIR2DL5A) (AA 161-210) antibodyKIR2DL5A 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 5A (KIR2DL5A) (AA 22-375) antibodyKIR2DL5A 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 5A (KIR2DL5A) (C-Term) antibodyKIR2DL5A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
- 说明
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The purified antibody is conjugated with cross-linked Allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.
- 限制
- 仅限研究用
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- 缓冲液
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- The purified antibody is conjugated with cross-linked Allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.
- 储存条件
- 4 °C
- 储存方法
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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- 抗原
- KIR2DL5A (Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 5A (KIR2DL5A))
- 别名
- CD158f (KIR2DL5A 产品)
- 别名
- CD158F antibody, KIR2DL5 antibody, KIR2DL5.1 antibody, KIR2DL5.3 antibody, KIR2DL5B antibody, killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 5A antibody, KIR2DL5A antibody
- 背景
- Killer cell immunoglobulin like receptor, two Ig d,CD158f, also known as KIR2DL5, is a polymorphic 60 kDa transmembrane glycoprotein with two Ig-like extracellular domains by which it recognize HLA class I molecules. Its long intracellular domain contains immunoreceptor tyrosine-based inhibitory motifs (ITIMs) that upon extracellular ligand-mediated phosphorylation serve as docking sites for inhibitory phosphatases, which results in blocking natural cytotoxicity as well as antibody-dependent cytotoxicity of the particular NK cell, and its adhesion toward target cells. Together with other killer inhibitory receptors CD158f is important for immunological tolerance to discriminate between normal and abnormal cells. Besides NK cells it is expressed on a small population of cytotoxic T cells. Expression of CD158f alleles is highly variable in the population.,KIR2DL5A
- 基因ID
- 57292
- UniProt
- Q8N109
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