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- 抗原 See all CHM 抗体
- CHM (Choroideremia (Rab Escort Protein 1) (CHM))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CHM antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 纯化方法
- Antigen affinity purified
- 免疫原
- A recombinant human protein corresponding to amino acids A193-Q380 was used as the immunogen for the CHM antibody.
- 亚型
- IgG
- Top Product
- Discover our top product CHM Primary Antibody
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anti-Choroideremia (Rab Escort Protein 1) (CHM) (C-Term) antibody
CHM 适用: 人, 大鼠, 小鼠, 马, 绵羊, 兔, Pig, 猴, Hamster, 豚鼠, 山羊, 驴, 犬, Cow, 小鸡, Cat, Avian WB 宿主: 山羊 Polyclonal unconjugated
anti-Choroideremia (Rab Escort Protein 1) (CHM) (AA 1-653) antibodyCHM 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Choroideremia (Rab Escort Protein 1) (CHM) (AA 1-80) antibodyCHM 适用: 人, 大鼠, 小鼠, 马, 绵羊, 兔, Pig, 猴, Hamster, 豚鼠, 山羊, 驴, 犬, Cow, 小鸡, Cat, Avian WB 宿主: 山羊 Polyclonal unconjugated
anti-Choroideremia (Rab Escort Protein 1) (CHM) (AA 35-84) antibodyCHM 适用: 人, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-Choroideremia (Rab Escort Protein 1) (CHM) (AA 120-210) antibodyCHM 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Choroideremia (Rab Escort Protein 1) (CHM) antibodyCHM 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Choroideremia (Rab Escort Protein 1) (CHM) (AA 292-320) antibodyCHM 适用: 人 WB 宿主: 兔 Polyclonal RB42411 unconjugated
anti-Choroideremia (Rab Escort Protein 1) (CHM) (N-Term) antibodyCHM 适用: 人, 马 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal dilution of the CHM antibody should be determined by the researcher.\. Western Blot: 0.5-1 μg/mL,Direct ELISA: 0.1-0.5 μg/mL
- 限制
- 仅限研究用
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- 缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- 储存条件
- -20 °C
- 储存方法
- After reconstitution, the CHM antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- 抗原
- CHM (Choroideremia (Rab Escort Protein 1) (CHM))
- 别名
- CHM / Choroideremia protein (CHM 产品)
- 别名
- CHM antibody, REP1 antibody, DXS540 antibody, GGTA antibody, HSD-32 antibody, REP-1 antibody, TCD antibody, DKFZp459K2154 antibody, tcd antibody, ggta antibody, rep-1 antibody, dxs540 antibody, hsd-32 antibody, MGC68578 antibody, Rep-1 antibody, chm antibody, chm-a antibody, chm-b antibody, chml antibody, CHM, Rab escort protein 1 antibody, choroideremia (Rab escort protein 1) antibody, choroideremia (Rab escort protein 1) L homeolog antibody, choroidermia (RAB escort protein 1) antibody, choroideremia (Rab escort protein 1) S homeolog antibody, CHM antibody, chm antibody, chm.L antibody, Chm antibody, chm.S antibody
- 背景
- Rab escort protein 1 (REP1) also known as rab proteins geranylgeranyltransferase component A 1 is an enzyme that in humans is encoded by the CHM gene. This gene encodes component A of the RAB geranylgeranyl transferase holoenzyme. In the dimeric holoenzyme, this subunit binds unprenylated Rab GTPases and then presents them to the catalytic Rab GGTase subunit for the geranylgeranyl transfer reaction. Rab GTPases need to be geranylgeranyled on either one or two cysteine residues in their C-terminus to localize to the correct intracellular membrane. Mutations in this gene are a cause of choroideremia, also known as tapetochoroidal dystrophy (TCD). This X-linked disease is characterized by progressive dystrophy of the choroid, retinal pigment epithelium and retina. Alternatively spliced transcript variants have been found for this gene.
- UniProt
- P24386
- 途径
- Sensory Perception of Sound
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