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NLRP3 抗体 (N-Term)

The 山羊 多克隆 anti-NLRP3 antibody is suitable to detect NLRP3 in samples from 人. It has been validated for ELISA 和 IHC.
产品编号 ABIN570839
发货至: 中国
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Quick Overview for NLRP3 抗体 (N-Term) (ABIN570839)

抗原

See all NLRP3 抗体
NLRP3 (NLR Family, Pyrin Domain Containing 3 (NLRP3))

适用

  • 102
  • 44
  • 30
  • 15
  • 5
  • 3
  • 1
  • 1
  • 1

宿主

  • 93
  • 18
  • 1
  • 1
山羊

克隆类型

  • 77
  • 36
多克隆

标记

  • 56
  • 10
  • 7
  • 6
  • 3
  • 3
  • 3
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  • 3
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  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This NLRP3 antibody is un-conjugated

应用范围

  • 68
  • 39
  • 25
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  • 12
  • 6
  • 5
  • 1
  • 1
  • 1
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  • 1
ELISA, Immunohistochemistry (IHC)

质量等级

Verified
  • 抗原表位

    • 8
    • 8
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    原理

    Cryopirin / NALP3 / NLRP3

    序列

    RDLYEKAKRD EPK

    特异性

    This antibody is expected to recognize all reported isoforms (NP_004886.3, NP_899632.1, NP_001120933.1, NP_001120934.1). Reported variants NP_001073289.1 and NP_004886.3 represent identical protein.

    交叉反应

    纯化方法

    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

    免疫原

    Peptide with sequence RDLYEKAKRDEPK-C, from the N-Terminus (near) of the protein sequence according to NP_004886.3, NP_899632.1, NP_001120933.1, NP_001120934.1.

    亚型

    IgG
  • 应用备注

    Immunohistochemistry: Paraffin embedded Human peripheral blood leukocytes. Recommended concentration: 5 μg/mL.

    Western Blot: Preliminary experiments gave an approx 36 kDa band in Human Peripheral Blood Mononucleocytes lysates and in lysates of cell line MOLT4, after 0.3-1 μg/mL antibody staining. Please note that currently we cannot find an explanation in the liter

    Peptide ELISA: antibody detection limit dilution 1:32000.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Minimize freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.
  • 抗原

    NLRP3 (NLR Family, Pyrin Domain Containing 3 (NLRP3))

    别名

    NLRP3

    背景

    NLRP3, NLR family, pyrin domain containing 3, AGTAVPRL, AII, AII/AVP, AVP, C1orf7, CIAS1, CLR1.1, FCAS, FCU, FLJ95925, MWS, NALP3, PYPAF1, AII/AVP receptor-like, NACHT domain-, leucine-rich repeat-, and PYD-containing protein 3, NACHT, LRR and PYD contain

    基因ID

    114548

    NCBI登录号

    NP_004886, NP_899632, NP_001120933, NP_001120934

    途径

    Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Inflammasome
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