NLRP3 抗体 (N-Term)
Quick Overview for NLRP3 抗体 (N-Term) (ABIN570839)
抗原
See all NLRP3 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
-
-
抗原表位
- N-Term
-
原理
- Cryopirin / NALP3 / NLRP3
-
序列
- RDLYEKAKRD EPK
-
特异性
- This antibody is expected to recognize all reported isoforms (NP_004886.3, NP_899632.1, NP_001120933.1, NP_001120934.1). Reported variants NP_001073289.1 and NP_004886.3 represent identical protein.
-
交叉反应
- 人
-
纯化方法
- Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
-
免疫原
- Peptide with sequence RDLYEKAKRDEPK-C, from the N-Terminus (near) of the protein sequence according to NP_004886.3, NP_899632.1, NP_001120933.1, NP_001120934.1.
-
亚型
- IgG
-
-
-
-
应用备注
-
Immunohistochemistry: Paraffin embedded Human peripheral blood leukocytes. Recommended concentration: 5 μg/mL.
Western Blot: Preliminary experiments gave an approx 36 kDa band in Human Peripheral Blood Mononucleocytes lysates and in lysates of cell line MOLT4, after 0.3-1 μg/mL antibody staining. Please note that currently we cannot find an explanation in the liter
Peptide ELISA: antibody detection limit dilution 1:32000.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.5 mg/mL
-
缓冲液
- Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Minimize freezing and thawing.
-
储存条件
- -20 °C
-
储存方法
- Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.
-
-
- NLRP3 (NLR Family, Pyrin Domain Containing 3 (NLRP3))
-
别名
- NLRP3
-
背景
- NLRP3, NLR family, pyrin domain containing 3, AGTAVPRL, AII, AII/AVP, AVP, C1orf7, CIAS1, CLR1.1, FCAS, FCU, FLJ95925, MWS, NALP3, PYPAF1, AII/AVP receptor-like, NACHT domain-, leucine-rich repeat-, and PYD-containing protein 3, NACHT, LRR and PYD contain
-
基因ID
- 114548
-
NCBI登录号
- NP_004886, NP_899632, NP_001120933, NP_001120934
-
途径
- Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Inflammasome
抗原
-