PEBP1 抗体
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- 抗原 See all PEBP1 抗体
- PEBP1 (Phosphatidylethanolamine Binding Protein 1 (PEBP1))
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PEBP1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- Antigen affinity purified
- 免疫原
- Amino acids DHRGKFKVASFRKKYELRAPVAGTCYQAEWDDYVPKLYEQ were used as the immunogen for the RKIP antibody.
- 亚型
- IgG
- Top Product
- Discover our top product PEBP1 Primary Antibody
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anti-Phosphatidylethanolamine Binding Protein 1 (PEBP1) (AA 2-187) antibody
PEBP1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Phosphatidylethanolamine Binding Protein 1 (PEBP1) (AA 2-187) antibodyPEBP1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Phosphatidylethanolamine Binding Protein 1 (PEBP1) (C-Term) antibodyVerified PEBP1 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Phosphatidylethanolamine Binding Protein 1 (PEBP1) (C-Term) antibodyPEBP1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Phosphatidylethanolamine Binding Protein 1 (PEBP1) (AA 1-187) antibodyPEBP1 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Phosphatidylethanolamine Binding Protein 1 (PEBP1) (AA 97-128) antibodyPEBP1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Phosphatidylethanolamine Binding Protein 1 (PEBP1) antibodyPEBP1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Phosphatidylethanolamine Binding Protein 1 (PEBP1) (AA 1-187) antibodyPEBP1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1D3-1B6 unconjugated
anti-Phosphatidylethanolamine Binding Protein 1 (PEBP1) (AA 1-30), (N-Term) antibodyPEBP1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB3718 unconjugated
anti-Phosphatidylethanolamine Binding Protein 1 (PEBP1) (AA 137-167) antibodyPEBP1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB3719 unconjugated
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- 应用备注
- Optimal dilution of the RKIP antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,IHC (FFPE): 1-2 μg/mL
- 限制
- 仅限研究用
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- 缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- 储存条件
- -20 °C
- 储存方法
- After reconstitution, the RKIP antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- 抗原
- PEBP1 (Phosphatidylethanolamine Binding Protein 1 (PEBP1))
- 别名
- RKIP / PEBP1 / PBP (PEBP1 产品)
- 别名
- HCNP antibody, HCNPpp antibody, PBP antibody, PEBP antibody, PEBP-1 antibody, RKIP antibody, pbp antibody, hcnp antibody, pebp antibody, rkip antibody, Pbp antibody, Pbp1 antibody, Pbpr antibody, Rkip antibody, PEBP1 antibody, BcDNA:LP12095 antibody, CG18594 antibody, Dmel\\CG18594 antibody, T2 antibody, zgc:56033 antibody, zgc:76942 antibody, phosphatidylethanolamine binding protein 1 antibody, phosphatidylethanolamine binding protein 1 L homeolog antibody, phosphatidylethanolamine-binding protein antibody, phosphatidylethanolamine-binding protein,putative antibody, Phosphatidylethanolamine-binding protein 1 antibody, PEBP1 antibody, pebp1 antibody, Pebp1 antibody, pebp1.L antibody, RR_RS07785 antibody, PVX_235290 antibody, PVX_123630 antibody, PKH_143640 antibody, EAM_1207 antibody
- 背景
- PEBP1 (Phosphatidylethanolamine-binding protein 1), also called PBP, RKIP, inhibits the phosphorylation and activation of MEK by RAF1. PEBP1 is identical to the phosphatidylethanolamine-binding protein (PBP) with a relative molecular mass of 23 kD. The PEBP1 gene is mapped on 12q24.23. PEBP1 coimmunoprecipitates with RAF1 and MEK from cell lysates and colocalizes with RAF1 when examined by confocal microscopy. PEBP1 overexpression interferes with the activation of MEK and ERK, induction of AP1-dependent reporter genes, and transformation elicited by an oncogenically activated RAF1 kinase. PEBP1 expression was rapidly upregulated during induction of chemotherapy-triggered apoptosis in human prostate and breast cancer cell lines, and maximal RKIP expression correlated perfectly with the onset of apoptosis by Chatterjee et al (2004). RKIP depletion decreased the mitotic index, the number of metaphase cells, traversal times from nuclear envelope breakdown to anaphase, and an override of mitotic checkpoints induced by spindle poisons.
- UniProt
- P30086
- 途径
- Feeding Behaviour
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