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CD14 抗体 (AA 16-260)

This anti-CD14 antibody is a 兔 多克隆 antibody detecting CD14 in WB, IHC (p) 和 ELISA (Capture). Suitable for 小鼠 和 大鼠.
产品编号 ABIN5708067
发货至: 中国

Quick Overview for CD14 抗体 (AA 16-260) (ABIN5708067)

抗原

See all CD14 抗体
CD14

适用

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小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This CD14 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA (Capture)
  • 抗原表位

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    AA 16-260

    纯化方法

    Antigen affinity purified

    免疫原

    A recombinant mouse protein corresponding to amino acids S16-A260 was used as the immunogen for the CD14 antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the CD14 antibody should be determined by the researcher.\. Western Blot: 0.5-1 μg/mL,IHC (FFPE): 1-2 μg/mL,ELISA (Capture, recombinant mouse protein): 0.1-0.5 μg/mL (BSA-free formulation available)

    限制

    仅限研究用
  • 缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    -20 °C

    储存方法

    After reconstitution, the CD14 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原

    CD14

    别名

    CD14

    背景

    CD14 is a single-copy gene encoding 2 protein forms: a 50- to 55 kDa glycosylphosphatidylinositol-anchored membrane protein (mCD14) and a monocyte or liver-derived soluble serum protein (sCD14) that lacks the anchor. This gene is located at bands 5q23-q31. The protein encoded by this gene is a surface antigen that is preferentially expressed on monocytes/macrophages. CD14 acts as a co-receptor (along with the Toll-like receptor TLR 4 and MD-2) for the detection of bacterial lipopolysaccharide (LPS). CD14 can bind LPS only in the presence of lipopolysaccharide-binding protein (LBP). Although LPS is considered its main ligand, CD14 also recognizes other pathogen-associated molecular patterns.

    UniProt

    P10810

    途径

    TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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