PARP1 抗体 (N-Term)
Quick Overview for PARP1 抗体 (N-Term) (ABIN5706805)
抗原
See all PARP1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- N-Term
-
Supplier Product No.
- 200-401-gm8
-
Supplier
- Rockland
-
原理
- PARP1 (N-term ZF1) Antibody
-
交叉反应 （详细）
- This antibody is specific for human PARP1 protein.
-
产品特性
- Synonyms: rabbit anti-PARP1 Antibody, Poly [ADP-ribose] polymerase 1, ADP-ribosyltransferase diphtheria toxin-like 1, ARTD1, NAD(+) ADP-ribosyltransferase 1, ADPRT 1, PPOL
-
纯化方法
- PARP1 (N-term ZF1) was purified from monospecific antiserum by immunoaffinity chromatography using protein A coupled to agarose beads.
-
过滤
- Sterile filtered
-
免疫原
-
Immunogen: PARP1 (N-term ZF1) purified antibody was prepared from whole rabbit serum produced by repeated immunizations with n-terminus region of human PARP1 zinc finger domain recombinant protein.
Immunogen Type: Recombinant Protein
-
亚型
- IgG
-
-
anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (AA 81-390) antibody
PARP1 适用: 人 WB, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) antibodyKO Validated PARP1 适用: 人 WB, IP, IF, ICC, IHC (p), ChIP 宿主: 兔 Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (AA 201-300) antibodyPARP1 适用: 人, 小鼠, 大鼠, 小鸡 WB, ELISA, FACS, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (AA 661-881) antibodyPARP1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (AA 1-100) antibodyPARP1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3G4 unconjugated
anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (AA 670-858) antibodyPARP1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) antibodyPARP1 适用: 人 WB, ELISA, IHC, IF, FACS 宿主: 兔 Monoclonal 8C7 unconjugated Recombinant Antibody
anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (cleaved) antibodyPARP1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (C-Term) antibodyPARP1 适用: 人 WB, 2D-PAGE 宿主: 兔 Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (AA 183-214) antibodyPARP1 适用: 人 WB, ELISA, IF, FACS 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Immunohistochemistry Dilution: 1:100
Application Note: Anti-PARP1 (N-term ZF1) antibody has been validated by western blotting, IHC, and nanoimmunoassay (NIA). Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 113 kDa in size corresponding to PARP-1 by western blotting in the appropriate cell lysate or extract.
Western Blot Dilution: 1:1000
Other: nanoimmunoassay (NIA): User Optimized
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1.0 mg/mL
-
缓冲液
-
Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide -
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
-
有效期
- 12 months
-
-
- PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))
-
别名
- PARP1
-
背景
- Background: PARP1 is the primary member of the poly(ADP-ribose) polymerase family, whose function is to signal DNA damage (and to recruit repair proteins) by PARylation. PARP1 is also involved in multiple cell death pathways, including apoptosis, necroptosis, autophagy, and a relatively new pathway termed parthanatos. It has been implicated in a new form of cell death termed parthanatos. PARP1 can also promote tissue survival by shifting the balance of cell death programs between autophagy and necrosis. Clinical studies have shown vulnerability to PARP inhibitors in DNA repair defective cancers. Anti-PARP1 (N-term ZF1) antibody is useful for researchers interested in cellular processes including DNA damage, transcriptional control, and stem cell identity research.
-
基因ID
- 142
-
UniProt
- P09874
-
途径
- Apoptosis, Caspase Cascade in Apoptosis, DNA Damage Repair, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location
抗原
-
