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REST 抗体

REST 适用: 人 WB, ELISA, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5706085
发货至: 中国
  • 抗原 See all REST 抗体
    REST (RE1-Silencing Transcription Factor (REST))
    适用
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    宿主
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    克隆类型
    • 46
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    多克隆
    标记
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    This REST antibody is un-conjugated
    应用范围
    • 32
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    Western Blotting (WB), ELISA, Immunoprecipitation (IP)
    免疫原
    RE1-silencing transcription factor
    亚型
    IgG
    Top Product
    Discover our top product REST Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze / thaw cycles.
    储存条件
    -20 °C
    有效期
    12 months
  • 抗原
    REST (RE1-Silencing Transcription Factor (REST))
    别名
    REST (REST 产品)
    别名
    NRSF antibody, XBR antibody, 2610008J04Rik antibody, AA407358 antibody, xbr antibody, nrsf antibody, rest antibody, resta antibody, REST antibody, RE1 silencing transcription factor antibody, RE1-silencing transcription factor antibody, RE1-silencing transcription factor S homeolog antibody, REST antibody, Rest antibody, rest.S antibody, rest antibody, LOC615792 antibody
    背景
    Synonyms:NRSF, REST, X2 box repressor, XBR Background:Transcriptional repressor which binds neuron-restrictive silencer element(NRSE) and represses neuronal gene transcription in non-neuronal cells. Restricts the expression of neuronal genes by associating with two distinct corepressors, mSin3 and CoREST, which in turn recruit histone deacetylase to the promoters of REST-regulated genes. Mediates repression by recruiting the BHC complex at RE1/NRSE sites which acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier. Transcriptional repression by REST-CDYL via the recruitment of histone methyltransferase EHMT2 may be important in transformation suppression.
    基因ID
    5978
    UniProt
    Q13127
    途径
    Negative Regulation of Hormone Secretion, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Chromatin Binding, Positive Regulation of Endopeptidase Activity
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