TELO2 抗体
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- 抗原 See all TELO2 抗体
- TELO2 (TEL2, Telomere Maintenance 2, Homolog (TELO2))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This TELO2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
- 免疫原
- TEL2, telomere maintenance 2, homolog (S. cerevisiae)
- 亚型
- IgG2a
- Top Product
- Discover our top product TELO2 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 说明
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A431 cells were subjected to SDS PAGE followed by western blot with FNab08592(TELO2 antibody) at dilution of 1:500
- 限制
- 仅限研究用
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- 缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze / thaw cycles.
- 储存条件
- -20 °C
- 有效期
- 12 months
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- 抗原
- TELO2 (TEL2, Telomere Maintenance 2, Homolog (TELO2))
- 别名
- TELO2 (TELO2 产品)
- 别名
- RGD1305553 antibody, 1200003M09Rik antibody, AI415602 antibody, Tel2 antibody, mKIAA0683 antibody, CLK2 antibody, TEL2 antibody, telomere maintenance 2 antibody, Telo2 antibody, TELO2 antibody
- 背景
- Synonyms:KIAA0683 Background:Regulator of the DNA damage response(DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase(PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation(IR), ultraviolet(UV) and mitomycin C(MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals. May be involved in telomere length regulation.
- 基因ID
- 9894
- UniProt
- Q9Y4R8
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