CCDC22 抗体
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- 抗原 See all CCDC22 抗体
- CCDC22 (Coiled-Coil Domain Containing 22 (CCDC22))
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CCDC22 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 免疫原
- coiled-coil domain containing 22
- 亚型
- IgG
- Top Product
- Discover our top product CCDC22 Primary Antibody
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anti-Coiled-Coil Domain Containing 22 (CCDC22) (C-Term) antibody
CCDC22 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Coiled-Coil Domain Containing 22 (CCDC22) (N-Term) antibodyCCDC22 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Coiled-Coil Domain Containing 22 (CCDC22) (AA 530-558), (C-Term) antibodyCCDC22 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB33346 unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze / thaw cycles.
- 储存条件
- -20 °C
- 有效期
- 12 months
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- 抗原
- CCDC22 (Coiled-Coil Domain Containing 22 (CCDC22))
- 别名
- CCDC22 (CCDC22 产品)
- 别名
- CXorf37 antibody, AI481216 antibody, DXImx40e antibody, Ppp1r3f antibody, Sfc22 antibody, RGD1560910 antibody, zgc:114058 antibody, coiled-coil domain containing 22 antibody, CCDC22 antibody, Ccdc22 antibody, ccdc22 antibody
- 背景
- Synonyms:CXorf37 Background:Involved in regulation of NF-kappa-B signaling. Promotes ubiquitination of I-kappa-B-kinase subunit IKBKB and its subsequent proteasomal degradation leading to NF-kappa-B activation, the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. May down-regulate NF-kappa-B activity via assocation with COMMD1 and involving a CUL2-dependent E3 ubiquitin ligase complex. Regulates the cellular localization of COMM domain-containing proteins, such as COMMD1 and COMMD10(PubMed:23563313). Plays a role in copper ion homeostasis. Involved in copper-dependent ATP7A trafficking between the trans-Golgi network and vesicles in the cell periphery, the function is proposed to depend on its association within the CCC complex and cooperation with the WASH complex on early endosomes(PubMed:25355947).
- 分子量
- 71 kDa
- 基因ID
- 28952
- UniProt
- O60826
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