TBC1D5 抗体
TBC1D5
适用: 人, 小鼠, 大鼠
WB, ELISA, IP, IHC
宿主: 兔
Polyclonal
unconjugated
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- 抗原 See all TBC1D5 抗体
- TBC1D5 (TBC1 Domain Family, Member 5 (TBC1D5))
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TBC1D5 antibody is un-conjugated
- 应用范围
- Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunohistochemistry (IHC)
- 免疫原
- TBC1 domain family, member 5
- 亚型
- IgG
- Top Product
- Discover our top product TBC1D5 Primary Antibody
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anti-TBC1 Domain Family, Member 5 (TBC1D5) (AA 446-795) antibody
TBC1D5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 说明
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A431 cells were subjected to SDS PAGE followed by western blot with FNab08515(TBC1D5 antibody) at dilution of 1:400
- 限制
- 仅限研究用
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- 缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze / thaw cycles.
- 储存条件
- -20 °C
- 有效期
- 12 months
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- 抗原
- TBC1D5 (TBC1 Domain Family, Member 5 (TBC1D5))
- 别名
- TBC1D5 (TBC1D5 产品)
- 别名
- RGD1561626 antibody, 1600014N05Rik antibody, mKIAA0210 antibody, TBC1 domain family, member 5 antibody, TBC1 domain family member 5 antibody, Tbc1d5 antibody, TBC1D5 antibody
- 背景
- Synonyms:KIAA0210 Background:May act as a GTPase-activating protein(GAP) for Rab family protein(s). May act as a GAP for RAB7A. Can displace RAB7A and retromer CSC subcomplex from the endosomal membrane to the cytosol, at least retromer displacement seems to require its catalytic activity(PubMed:19531583, PubMed:20923837). Required for retrograde transport of cargo proteins from endosomes to the trans-Golgi network(TGN), the function seems to require its catalytic activity. Involved in regulation of autophagy(PubMed:22354992). May act as a molecular switch between endosomal and autophagosomal transport and is involved in reprogramming vesicle trafficking upon autophagy induction. Involved in the trafficking of ATG9A upon activation of autophagy. May regulate the recruitment of ATG9A-AP2-containing vesicles to autophagic membranes(PubMed:24603492).
- 基因ID
- 9779
- UniProt
- Q92609
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