SRGAP2 抗体
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- 抗原 See all SRGAP2 抗体
- SRGAP2 (SLIT-ROBO rho GTPase Activating Protein 2 (SRGAP2))
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SRGAP2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 免疫原
- SLIT-ROBO Rho GTPase activating protein 2
- 亚型
- IgG
- Top Product
- Discover our top product SRGAP2 Primary Antibody
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- 应用备注
- WB : 1:500-1:5000 IP : 1:500-1:5000 IHC : 1:20-1:200
- 说明
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mouse kidney tissue were subjected to SDS PAGE followed by western blot with FNab08225(SRGAP2 antibody) at dilution of 1:1000
- 限制
- 仅限研究用
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- 缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze / thaw cycles.
- 储存条件
- -20 °C
- 有效期
- 12 months
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- 抗原
- SRGAP2 (SLIT-ROBO rho GTPase Activating Protein 2 (SRGAP2))
- 别名
- SRGAP2 (SRGAP2 产品)
- 别名
- ARHGAP34 antibody, FNBP2 antibody, SRGAP2A antibody, SRGAP3 antibody, 9930124L22Rik antibody, AI448945 antibody, FBP2 antibody, Fnbp2 antibody, srGAP3 antibody, AI452337 antibody, Arhgap14 antibody, D130026O08Rik antibody, Gbi antibody, MEGAP antibody, WRP antibody, mKIAA0411 antibody, RGD1566016 antibody, srGAP2 antibody, srgap2a antibody, wu:fb47h12 antibody, zgc:136814 antibody, fnbp2 antibody, srgap2 antibody, SLIT-ROBO Rho GTPase activating protein 2 antibody, SLIT-ROBO Rho GTPase activating protein 3 antibody, SLIT-ROBO Rho GTPase activating protein 2 L homeolog antibody, SRGAP2 antibody, Srgap2 antibody, Srgap3 antibody, srgap2 antibody, srgap2.L antibody
- 背景
- Synonyms:ARHGAP34, FNBP2, Formin binding protein 2, KIAA0456, SRGAP2, srGAP3 Background:RAC1 GTPase activating protein(GAP) that binds and deforms membranes, and regulates actin dynamics to regulate cell migration and differentiation. Plays an important role in different aspects of neuronal morphogenesis and migration mainly during development of the cerebral cortex. This includes the biogenesis of neurites, where it is required for both axons and dendrites outgrowth, and the maturation of the dendritic spines. Also stimulates the branching of the leading process and negatively regulates neuron radial migration in the cerebral cortex. Its interaction and inhibition by SRGAP2C reduces the rate of spine maturation, alters dendritic spine morphology and density and indirectly increases neuronal migration. It may have implications for cognition, learning and memory. In non-neuronal cells, it may also play a role in cell migration by regulating the formation of lamellipodia and filopodia.
- 分子量
- 130 kDa
- 基因ID
- 23380
- UniProt
- O75044
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