TRIM33 抗体
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- 抗原 See all TRIM33 抗体
- TRIM33 (Tripartite Motif Containing 33 (TRIM33))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TRIM33 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 免疫原
- tripartite motif-containing 33
- 亚型
- IgG
- Top Product
- Discover our top product TRIM33 Primary Antibody
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- 应用备注
- WB:1:200-1:2000
- 说明
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COLO 320 cells were subjected to SDS PAGE followed by western blot with FNab08981(TRIM33 antibody) at dilution of 1:500
- 限制
- 仅限研究用
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- 缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze / thaw cycles.
- 储存条件
- -20 °C
- 有效期
- 12 months
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- 抗原
- TRIM33 (Tripartite Motif Containing 33 (TRIM33))
- 别名
- TRIM33 (TRIM33 产品)
- 别名
- TRIM33 antibody, ptc7 antibody, rfg7 antibody, tf1g antibody, tif1g antibody, tifgamma antibody, MGC146665 antibody, tif1gamma antibody, ECTO antibody, PTC7 antibody, RFG7 antibody, TF1G antibody, TIF1G antibody, TIF1GAMMA antibody, TIFGAMMA antibody, ecto antibody, 8030451N04Rik antibody, AI413936 antibody, Ecto antibody, Tif1g antibody, ectodermin antibody, mKIAA1113 antibody, cb1085 antibody, id:ibd2175 antibody, mon antibody, wu:fc17f10 antibody, zgc:136680 antibody, tripartite motif containing 33 antibody, tripartite motif containing 33 L homeolog antibody, tripartite motif-containing 33 antibody, TRIM33 antibody, trim33 antibody, trim33.L antibody, Trim33 antibody
- 背景
- Synonyms:Ectodermin homolog, FLJ32925, KIAA1113, Protein Rfg7, PTC7, RET fused gene 7 protein, RFG7, TF1G, TIF1 gamma, TIF1G, TIF1GAMMA, TIFGAMMA, TRIM33, tripartite motif containing 33 Background:Acts as an E3 ubiquitin-protein ligase. Promotes SMAD4 ubiquitination, nuclear exclusion and degradation via the ubiquitin proteasome pathway. According to PubMed:16751102, does not promote a decrease in the level of endogenous SMAD4. May act as a transcriptional repressor. Inhibits the transcriptional response to TGF-beta/BMP signaling cascade. Plays a role in the control of cell proliferation. Its association with SMAD2 and SMAD3 stimulates erythroid differentiation of hematopoietic stem/progenitor(By similarity). Monoubiquitinates SMAD4 and acts as an inhibitor of SMAD4-dependent TGF-beta/BMP signaling cascade(Monoubiquitination of SMAD4 hampers its ability to form a stable complex with activated SMAD2/3 resulting in inhibition of TGF-beta/BMP signaling cascade).
- 分子量
- 72kDa
- 基因ID
- 51592
- UniProt
- Q9UPN9
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