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NGEF 抗体

NGEF 适用: 人, 小鼠 WB, ELISA, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5703341
发货至: 中国
  • 抗原 See all NGEF 抗体
    NGEF (Neuronal Guanine Nucleotide Exchange Factor (NGEF))
    适用
    • 37
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    • 30
    • 4
    • 4
    • 4
    • 4
    人, 小鼠
    宿主
    • 44
    • 1
    克隆类型
    • 44
    • 1
    多克隆
    标记
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    • 2
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    This NGEF antibody is un-conjugated
    应用范围
    • 41
    • 26
    • 26
    • 12
    • 6
    • 6
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunoprecipitation (IP)
    免疫原
    neuronal guanine nucleotide exchange factor
    亚型
    IgG
    Top Product
    Discover our top product NGEF Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze / thaw cycles.
    储存条件
    -20 °C
    有效期
    12 months
  • 抗原
    NGEF (Neuronal Guanine Nucleotide Exchange Factor (NGEF))
    别名
    NGEF (NGEF 产品)
    别名
    Ephexin-1 antibody, ARHGEF27 antibody, EPHEXIN antibody, Tims2 antibody, ephexin antibody, Besh3 antibody, ephexin-1 antibody, neuronal guanine nucleotide exchange factor antibody, NGEF antibody, Ngef antibody
    背景
    Synonyms: Background:Acts as a guanine nucleotide exchange factor(GEF) which differentially activates the GTPases RHOA, RAC1 and CDC42. Plays a role in axon guidance regulating ephrin-induced growth cone collapse and dendritic spine morphogenesis. Upon activation by ephrin through EPHA4, the GEF activity switches toward RHOA resulting in its activation. Activated RHOA promotes cone retraction at the expense of RAC1-and CDC42-stimulated growth cone extension(By similarity).
    分子量
    75 kDa
    基因ID
    25791
    UniProt
    Q8N5V2
    途径
    Neurotrophin Signaling Pathway
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