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GNE 抗体

GNE 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5703183
发货至: 中国
  • 抗原 See all GNE 抗体
    GNE (Glucosamine (UDP-N-Acetyl)-2-Epimerase/N-Acetylmannosamine Kinase (GNE))
    适用
    • 54
    • 27
    • 19
    宿主
    • 53
    • 1
    克隆类型
    • 53
    • 1
    多克隆
    标记
    • 20
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    This GNE antibody is un-conjugated
    应用范围
    • 53
    • 29
    • 19
    • 13
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    • 6
    • 1
    • 1
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    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    免疫原
    glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
    亚型
    IgG
    Top Product
    Discover our top product GNE Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    说明

    Jurkat cells were subjected to SDS PAGE followed by western blot with FNab03544( GNE Antibody) at dilution of 1:1000

    限制
    仅限研究用
  • 缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze / thaw cycles.
    储存条件
    -20 °C
    有效期
    12 months
  • 抗原
    GNE (Glucosamine (UDP-N-Acetyl)-2-Epimerase/N-Acetylmannosamine Kinase (GNE))
    别名
    GNE (GNE 产品)
    别名
    DMRV antibody, GLCNE antibody, IBM2 antibody, UAE1 antibody, zgc:77657 antibody, GNE antibody, MGC145505 antibody, NM antibody, Uae1 antibody, 2310066H07Rik antibody, glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase antibody, GNE antibody, gne antibody, Gne antibody
    背景
    Synonyms:GLCNE Background:The protein encoded by this gene is a bifunctional enzyme that initiates and regulates the biosynthesis of N-acetylneuraminic acid (NeuAc), a precursor of sialic acids. It is a rate-limiting enzyme in the sialic acid biosynthetic pathway. Sialic acid modification of cell surface molecules is crucial for their function in many biologic processes, including cell adhesion and signal transduction. Differential sialylation of cell surface molecules is also implicated in the tumorigenicity and metastatic behavior of malignant cells. Mutations in this gene are associated with sialuria, autosomal recessive inclusion body myopathy, and Nonaka myopathy. Alternative splicing of this gene results in transcript variants encoding different isoforms.
    分子量
    79 kDa
    基因ID
    10020
    UniProt
    Q9Y223
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