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CDC34 抗体

CDC34 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5702689
发货至: 中国
  • 抗原 See all CDC34 抗体
    CDC34 (Cell Division Cycle 34 (CDC34))
    适用
    • 39
    • 25
    • 23
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠
    宿主
    • 35
    • 5
    克隆类型
    • 27
    • 13
    多克隆
    标记
    • 22
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This CDC34 antibody is un-conjugated
    应用范围
    • 18
    • 10
    • 5
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    免疫原
    cell division cycle 34 homolog (S. cerevisiae)
    亚型
    IgG
    Top Product
    Discover our top product CDC34 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    说明

    human pancreas tissue were subjected to SDS PAGE followed by western blot with FNab01527(CDC34 antibody) at dilution of 1:300

    限制
    仅限研究用
  • 缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze / thaw cycles.
    储存条件
    -20 °C
    有效期
    12 months
  • 抗原
    CDC34 (Cell Division Cycle 34 (CDC34))
    别名
    CDC34 (CDC34 产品)
    别名
    E2-CDC34 antibody, UBC3 antibody, UBCH3 antibody, UBE2R1 antibody, AI327276 antibody, e2-cdc34 antibody, ubc3 antibody, ube2r1 antibody, CDC34 antibody, DNA6 antibody, Ube2r2 antibody, zgc:55452 antibody, fb34h09 antibody, wu:fb34h09 antibody, wu:fe17e09 antibody, zgc:91847 antibody, cell division cycle 34 antibody, cell division cycle 34 L homeolog antibody, SCF E2 ubiquitin-protein ligase catalytic subunit CDC34 antibody, SCF E2 ubiquitin-protein ligase catalytic subunit antibody, cell division cycle 34 homolog (S. cerevisiae) a antibody, cell division cycle 34 homolog (S. cerevisiae) b antibody, CDC34 antibody, Cdc34 antibody, cdc34.L antibody, cdc34 antibody, cdc34a antibody, cdc34b antibody
    背景
    Synonyms:UBCH3, UBE2R1 Background:Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-linked polyubiquitination. Cooperates with the E2 UBCH5C and the SCF(FBXW11) E3 ligase complex for the polyubiquitination of NFKBIA leading to its subsequent proteasomal degradation. Performs ubiquitin chain elongation building ubiquitin chains from the UBE2D3-primed NFKBIA-linked ubiquitin. UBE2D3 acts as an initiator E2, priming the phosphorylated NFKBIA target at positions 'Lys-21' and/or 'Lys-22' with a monoubiquitin. Cooperates with the SCF(SKP2) E3 ligase complex to regulate cell proliferation through ubiquitination and degradation of MYBL2 and KIP1. Involved in ubiquitin conjugation and degradation of CREM isoform ICERIIgamma and ATF15 resulting in abrogation of ICERIIgamma-and ATF5-mediated repression of cAMP-induced transcription during both meiotic and mitotic cell cycles. Involved in the regulation of the cell cycle G2/M phase through its targeting of the WEE1 kinase for ubiquitination and degradation. Also involved in the degradation of beta-catenin. Is target of human herpes virus 1 protein ICP0, leading to ICP0-dependent dynamic interaction with proteasomes.
    分子量
    34 kDa
    基因ID
    997
    UniProt
    P49427
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