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FER 抗体

FER 适用: 人, 小鼠 WB, ELISA, IHC, IF, FACS 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5701552
发货至: 中国
  • 抗原 See all FER 抗体
    FER (FER Tyrosine Kinase (FER))
    适用
    • 70
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    人, 小鼠
    宿主
    • 91
    • 7
    克隆类型
    • 91
    • 7
    多克隆
    标记
    • 38
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    This FER antibody is un-conjugated
    应用范围
    • 76
    • 36
    • 26
    • 26
    • 14
    • 13
    • 11
    • 6
    • 4
    • 3
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    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
    免疫原
    fer (fps/fes related) tyrosine kinase
    亚型
    IgG
    Top Product
    Discover our top product FER Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    说明

    NIH/3T3 cells were subjected to SDS PAGE followed by western blot with FNab03076( FER Antibody) at dilution of 1:1000

    限制
    仅限研究用
  • 缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze / thaw cycles.
    储存条件
    -20 °C
    有效期
    12 months
  • 抗原
    FER (FER Tyrosine Kinase (FER))
    别名
    FER (FER 产品)
    别名
    FerT antibody, PPP1R74 antibody, TYK3 antibody, Fer antibody, Flk antibody, Flk_retired antibody, AV082135 antibody, C330004K01Rik antibody, Fert antibody, FER tyrosine kinase antibody, fer (fms/fps related) protein kinase antibody, FER antibody, Fer antibody
    背景
    Synonyms:TYK3 Background:Tyrosine-protein kinase that acts downstream of cell surface receptors for growth factors and plays a role in the regulation of the actin cytoskeleton, microtubule assembly, lamellipodia formation, cell adhesion, cell migration and chemotaxis. Acts downstream of EGFR, KIT, PDGFRA and PDGFRB. Acts downstream of EGFR to promote activation of NF-kappa-B and cell proliferation. May play a role in the regulation of the mitotic cell cycle. Plays a role in the insulin receptor signaling pathway and in activation of phosphatidylinositol 3-kinase. Acts downstream of the activated FCER1 receptor and plays a role in FCER1(high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Plays a role in the regulation of mast cell degranulation. Plays a role in leukocyte recruitment and diapedesis in response to bacterial lipopolysaccharide(LPS). Plays a role in synapse organization, trafficking of synaptic vesicles, the generation of excitatory postsynaptic currents and neuron-neuron synaptic transmission. Plays a role in neuronal cell death after brain damage. Phosphorylates CTTN, CTNND1, PTK2/FAK1, GAB1, PECAM1 and PTPN11. May phosphorylate JUP and PTPN1. Can phosphorylate STAT3, but the biological relevance of this depends on cell type and stimulus.
    分子量
    95 kDa
    基因ID
    2241
    UniProt
    P16591
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