USP19 抗体
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- 抗原 See all USP19 抗体
- USP19 (Ubiquitin Specific Peptidase 19 (USP19))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This USP19 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 免疫原
- ubiquitin specific peptidase 19
- 亚型
- IgG
- Top Product
- Discover our top product USP19 Primary Antibody
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- 应用备注
- WB : 1:200-1:2000,IP:1:200-1:2000
- 说明
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Jurkat cells were subjected to SDS PAGE followed by western blot with FNab09314( USP19 Antibody) at dilution of 1:600
- 限制
- 仅限研究用
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- 缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze / thaw cycles.
- 储存条件
- -20 °C
- 有效期
- 12 months
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- 抗原
- USP19 (Ubiquitin Specific Peptidase 19 (USP19))
- 别名
- USP19 (USP19 产品)
- 别名
- wu:fc26a05 antibody, si:dkey-32e6.9 antibody, USP19 antibody, MGC145127 antibody, ZMYND9 antibody, 8430421I07Rik antibody, AI047774 antibody, Zmynd9 antibody, ubiquitin specific peptidase 19 antibody, universal stress protein antibody, ubiquitin carboxyl-terminal hydrolase 19 antibody, usp19 antibody, USP19 antibody, RR_RS18085 antibody, PTRG_09611 antibody, Usp19 antibody
- 背景
- Synonyms:Deubiquitinating enzyme 19, KIAA0891, Ubiquitin thiolesterase 19, USP19, ZMYND9 Background:Deubiquitinating enzyme that regulates the degradation of various proteins. Deubiquitinates and prevents proteasomal degradation of RNF123 which in turn stimulates CDKN1B ubiquitin-dependent degradation thereby playing a role in cell proliferation. Involved in decreased protein synthesis in atrophying skeletal muscle. Modulates transcription of major myofibrillar proteins. Also involved in turnover of endoplasmic-reticulum-associated degradation(ERAD) substrates. Regulates the stability of BIRC2/c-IAP1 and BIRC3/c-IAP2 by preventing their ubiquitination. Required for cells to mount an appropriate response to hypoxia and rescues HIF1A from degradation in a non-catalytic manner. Plays an important role in 17 beta-estradiol(E2)-inhibited myogenesis. Decreases the levels of ubiquitinated proteins during skeletal muscle formation and acts to repress myogenesis. Exhibits a preference towards 'Lys-63'-linked Ubiquitin chains.
- 分子量
- 43kDa,Observed 70kDa,43kDa
- 基因ID
- 10869
- UniProt
- O94966
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