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LCAT 抗体

LCAT 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5701039
发货至: 中国
  • 抗原 See all LCAT 抗体
    LCAT (Lecithin-Cholesterol Acyltransferase (LCAT))
    适用
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    人, 小鼠, 大鼠
    宿主
    • 68
    • 4
    • 2
    克隆类型
    • 70
    • 4
    多克隆
    标记
    • 34
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    This LCAT antibody is un-conjugated
    应用范围
    • 70
    • 31
    • 30
    • 14
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    • 6
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    Western Blotting (WB), ELISA
    免疫原
    lecithin-cholesterol acyltransferase
    亚型
    IgG
    Top Product
    Discover our top product LCAT Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze / thaw cycles.
    储存条件
    -20 °C
    有效期
    12 months
  • 抗原
    LCAT (Lecithin-Cholesterol Acyltransferase (LCAT))
    别名
    LCAT (LCAT 产品)
    别名
    AI046659 antibody, D8Wsu61e antibody, MGC82035 antibody, lcat antibody, MGC88964 antibody, LCAT antibody, lecithin-cholesterol acyltransferase antibody, lecithin cholesterol acyltransferase antibody, lecithin-cholesterol acyltransferase L homeolog antibody, solute carrier family 12 member 4 antibody, fragile site, aphidicolin type, common, fra(13)(q13.2) antibody, LCAT antibody, Lcat antibody, lcat.L antibody, lcat antibody, SLC12A4 antibody, FRA13A antibody
    背景
    Synonyms: Background:Central enzyme in the extracellular metabolism of plasma lipoproteins. Synthesized mainly in the liver and secreted into plasma where it converts cholesterol and phosphatidylcholines(lecithins) to cholesteryl esters and lysophosphatidylcholines on the surface of high and low density lipoproteins(HDLs and LDLs)(PubMed:10329423, PubMed:19065001, PubMed:26195816). The cholesterol ester is then transported back to the liver. Has a preference for plasma 16:0-18:2 or 18:O-18:2 phosphatidylcholines(PubMed:8820107). Also produced in the brain by primary astrocytes, and esterifies free cholesterol on nascent APOE-containing lipoproteins secreted from glia and influences cerebral spinal fluid(CSF) APOE-and APOA1 levels. Together with APOE and the cholesterol transporter ABCA1, plays a key role in the maturation of glial-derived, nascent lipoproteins. Required for remodeling high-density lipoprotein particles into their spherical forms(PubMed:10722751).
    分子量
    55 kDa
    基因ID
    3931
    UniProt
    P04180
    途径
    Lipid Metabolism
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