FBXO2 抗体
-
- 抗原 See all FBXO2 抗体
- FBXO2 (F-Box Protein 2 (FBXO2))
-
适用
- 人, 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This FBXO2 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 免疫原
- F-box protein 2
- 亚型
- IgG
- Top Product
- Discover our top product FBXO2 Primary Antibody
-
-
- 应用备注
- Optimal working dilution should be determined by the investigator.
- 说明
-
SH-SY5Y cells were subjected to SDS PAGE followed by western blot with FNab03040( FBXO2 Antibody) at dilution of 1:300
- 限制
- 仅限研究用
-
- 缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze / thaw cycles.
- 储存条件
- -20 °C
- 有效期
- 12 months
-
- 抗原
- FBXO2 (F-Box Protein 2 (FBXO2))
- 别名
- FBXO2 (FBXO2 产品)
- 别名
- FBG1 antibody, FBX2 antibody, Fbs1 antibody, NFB42 antibody, OCP1 antibody, Fbs2 antibody, Prpl4 antibody, F-box protein 2 antibody, FBXO2 antibody, Fbxo2 antibody
- 背景
- Synonyms:FBX2 Background:Substrate recognition component of a SCF(SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Involved in the endoplasmic reticulum-associated degradation pathway(ERAD) for misfolded lumenal proteins by recognizing and binding sugar chains on unfolded glycoproteins that are retrotranslocated into the cytosol and promoting their ubiquitination and subsequent degradation. Prevents formation of cytosolic aggregates of unfolded glycoproteins that have been retrotranslocated into the cytosol. Able to recognize and bind denatured glycoproteins, preferentially those of the high-mannose type(By similarity).
- 分子量
- 33-40 kDa
- 基因ID
- 26232
- UniProt
- Q9UK22
-