FAM20C 抗体
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- 抗原 See all FAM20C 抗体
- FAM20C (Family with Sequence Similarity 20, Member C (FAM20C))
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适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FAM20C antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 免疫原
- family with sequence similarity 20, member C
- 亚型
- IgG
- Top Product
- Discover our top product FAM20C Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 说明
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mouse ovary tissue were subjected to SDS PAGE followed by western blot with FNab02979( FAM20C Antibody) at dilution of 1:300
- 限制
- 仅限研究用
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- 缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze / thaw cycles.
- 储存条件
- -20 °C
- 有效期
- 12 months
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- 抗原
- FAM20C (Family with Sequence Similarity 20, Member C (FAM20C))
- 别名
- FAM20C (FAM20C 产品)
- 别名
- DMP-4 antibody, DMP4 antibody, GEF-CK antibody, RNS antibody, C76981 antibody, mKIAA4081 antibody, RGD1311980 antibody, si:ch73-266a4.1 antibody, FAM20C, golgi associated secretory pathway kinase antibody, family with sequence similarity 20, member C antibody, family with sequence similarity 20, member Cb antibody, FAM20C antibody, Fam20c antibody, fam20cb antibody
- 背景
- Synonyms:Dentin matrix protein 4, DMP 4, DMP4, FAM20C, Protein FAM20C, RNS Background:Golgi serine/threonine protein kinase that phosphorylates secretory pathway proteins within Ser-x-Glu/pSer motifs and plays a key role in biomineralization of bones and teeth(PubMed:22582013, PubMed:23754375, PubMed:25789606). Constitutes the main protein kinase for extracellular proteins, generating the majority of the extracellular phosphoproteome(PubMed:26091039). Mainly phosphorylates proteins within the Ser-x-Glu/pSer motif, but also displays a broader substrate specificity(PubMed:26091039). Phosphorylates casein as well as a number of proteins involved in biomineralization such as AMELX, AMTN, ENAM and SPP1(PubMed:22582013, PubMed:25789606). In addition to its role in biomineralization, also plays a role in lipid homeostasis, wound healing and cell migration and adhesion(PubMed:26091039).
- 分子量
- 65-70 kDa
- 基因ID
- 56975
- UniProt
- Q8IXL6
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