DNAJC10 抗体
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- 抗原 See all DNAJC10 抗体
- DNAJC10 (DnaJ (Hsp40) Homolog, Subfamily C, Member 10 (DNAJC10))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DNAJC10 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 免疫原
- DnaJ (Hsp40) homolog, subfamily C, member 10
- 亚型
- IgG
- Top Product
- Discover our top product DNAJC10 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 说明
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HeLa cells were subjected to SDS PAGE followed by western blot with FNab02457(DNAJC10 antibody) at dilution of 1:1500
- 限制
- 仅限研究用
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- 缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze / thaw cycles.
- 储存条件
- -20 °C
- 有效期
- 12 months
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- 抗原
- DNAJC10 (DnaJ (Hsp40) Homolog, Subfamily C, Member 10 (DNAJC10))
- 别名
- DNAJC10 (DNAJC10 产品)
- 别名
- ERdj5 antibody, JPDI antibody, MTHr antibody, PDIA19 antibody, 1200006L06Rik antibody, D2Ertd706e antibody, dnajc10 antibody, zgc:162218 antibody, DnaJ heat shock protein family (Hsp40) member C10 antibody, DnaJ (Hsp40) homolog, subfamily C, member 10 antibody, DNAJC10 antibody, Dnajc10 antibody, dnajc10 antibody
- 背景
- Synonyms:ERDJ5 Background:Endoplasmic reticulum disulfide reductase involved both in the correct folding of proteins and degradation of misfolded proteins. Required for efficient folding of proteins in the endoplasmic reticulum by catalyzing the removal of non-native disulfide bonds formed during the folding of proteins, such as LDLR. Also involved in endoplasmic reticulum-associated degradation(ERAD) by reducing incorrect disulfide bonds in misfolded glycoproteins recognized by EDEM1. Interaction with HSPA5 is required its activity, not for the disulfide reductase activity, but to facilitate the release of DNAJC10 from its substrate. Promotes apoptotic signaling pathway in response to endoplasmic reticulum stress.
- 分子量
- 75-80 kDa
- 基因ID
- 54431
- UniProt
- Q8IXB1
- 途径
- Cell RedoxHomeostasis
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