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DPP4 抗体

DPP4 适用: 人, Hamster WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5700468
发货至: 中国
  • 抗原 See all DPP4 抗体
    DPP4 (Dipeptidyl-Peptidase 4 (DPP4))
    适用
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    人, Hamster
    宿主
    • 93
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    克隆类型
    • 88
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    多克隆
    标记
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    This DPP4 antibody is un-conjugated
    应用范围
    • 75
    • 68
    • 50
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    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    免疫原
    dipeptidyl-peptidase 4
    亚型
    IgG
    Top Product
    Discover our top product DPP4 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    说明

    PC-3 cells were subjected to SDS PAGE followed by western blot with FNab02520(DPP4 antibody) at dilution of 1:500

    限制
    仅限研究用
  • 缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze / thaw cycles.
    储存条件
    -20 °C
    有效期
    12 months
  • 抗原
    DPP4 (Dipeptidyl-Peptidase 4 (DPP4))
    别名
    DPP4 (DPP4 产品)
    别名
    ADABP antibody, ADCP2 antibody, CD26 antibody, DPPIV antibody, TP103 antibody, MGC81966 antibody, MOP9.8 antibody, MOP9_8 antibody, DPP4 antibody, si:ch73-2d23.3 antibody, Cd26 antibody, Dpp-4 antibody, THAM antibody, dipeptidyl peptidase 4 antibody, dipeptidyl-peptidase 4 S homeolog antibody, prolyl oligopeptidase family protein antibody, dipeptidyl-peptidase 4 antibody, dipeptidylpeptidase 4 antibody, DPP4 antibody, dpp4.S antibody, AT5G24260 antibody, dpp4 antibody, Dpp4 antibody
    背景
    Synonyms:ADABP, ADCP 2, ADCP2, CD26, dipeptidyl peptidase 4, Dipeptidyl peptidase IV, DPP IV, DPP4, DPPIV, T cell activation antigen CD26, TP103 Background:Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor(TCR)-mediated T-cell activation. Acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. Its binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Its interaction with ADA also regulates lymphocyte-epithelial cell adhesion. In association with FAP is involved in the pericellular proteolysis of the extracellular matrix(ECM), the migration and invasion of endothelial cells into the ECM. May be involved in the promotion of lymphatic endothelial cells adhesion, migration and tube formation. When overexpressed, enhanced cell proliferation, a process inhibited by GPC3. Acts also as a serine exopeptidase with a dipeptidyl peptidase activity that regulates various physiological processes by cleaving peptides in the circulation, including many chemokines, mitogenic growth factors, neuropeptides and peptide hormones. Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.
    分子量
    55-60 kDa
    基因ID
    1803
    UniProt
    P27487
    途径
    Peptide Hormone Metabolism, Regulation of Leukocyte Mediated Immunity
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