OAS2 抗体
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- 抗原 See all OAS2 抗体
- OAS2 (2'-5'-Oligoadenylate Synthetase 2, 69/71kDa (OAS2))
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This OAS2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)
- 免疫原
- 2'-5'-oligoadenylate synthetase 2, 69/71kDa
- 亚型
- IgG
- Top Product
- Discover our top product OAS2 Primary Antibody
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anti-2'-5'-Oligoadenylate Synthetase 2, 69/71kDa (OAS2) (AA 11-346) antibody
OAS2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-2'-5'-Oligoadenylate Synthetase 2, 69/71kDa (OAS2) (AA 11-346) antibodyOAS2 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C1 unconjugated
anti-2'-5'-Oligoadenylate Synthetase 2, 69/71kDa (OAS2) (AA 401-500) antibodyOAS2 适用: 小鼠 WB, ELISA, ICC, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-2'-5'-Oligoadenylate Synthetase 2, 69/71kDa (OAS2) (N-Term) antibodyOAS2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-2'-5'-Oligoadenylate Synthetase 2, 69/71kDa (OAS2) (AA 398-447) antibodyOAS2 适用: 人, Pig, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-2'-5'-Oligoadenylate Synthetase 2, 69/71kDa (OAS2) (AA 35-84) antibodyOAS2 适用: 人, Pig, 犬, 马, 猴, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-2'-5'-Oligoadenylate Synthetase 2, 69/71kDa (OAS2) (Internal Region) antibodyVerified OAS2 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-2'-5'-Oligoadenylate Synthetase 2, 69/71kDa (OAS2) (AA 357-371) antibodyVerified OAS2 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 说明
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Jurkat cells were subjected to SDS PAGE followed by western blot with FNab05951(OAS2 antibody) at dilution of 1:500
- 限制
- 仅限研究用
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- 缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze / thaw cycles.
- 储存条件
- -20 °C
- 有效期
- 12 months
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- 抗原
- OAS2 (2'-5'-Oligoadenylate Synthetase 2, 69/71kDa (OAS2))
- 别名
- OAS2 (OAS2 产品)
- 别名
- Oasl11 antibody, 2'-5'-oligoadenylate synthetase 2 antibody, 2'-5' oligoadenylate synthetase 2 antibody, 2'-5'-oligoadenylate synthetase 2, 69/71kDa antibody, OAS2 antibody, Oas2 antibody
- 背景
- Synonyms: Background:Interferon-induced, dsRNA-activated antiviral enzyme which plays a critical role in cellular innate antiviral response. In addition, it may also play a role in other cellular processes such as apoptosis, cell growth, differentiation and gene regulation. Synthesizes higher oligomers of 2'-5'-oligoadenylates(2-5A) from ATP which then bind to the inactive monomeric form of ribonuclease L(RNase L) leading to its dimerization and subsequent activation. Activation of RNase L leads to degradation of cellular as well as viral RNA, resulting in the inhibition of protein synthesis, thus terminating viral replication. Can mediate the antiviral effect via the classical RNase L-dependent pathway or an alternative antiviral pathway independent of RNase L.
- 分子量
- 66-71 kDa
- 基因ID
- 4939
- UniProt
- P29728
- 途径
- Hepatitis C
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