SPAG5 抗体
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- 抗原 See all SPAG5 抗体
- SPAG5 (Sperm Associated Antigen 5 (SPAG5))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SPAG5 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
- 免疫原
- sperm associated antigen 5
- 亚型
- IgG
- Top Product
- Discover our top product SPAG5 Primary Antibody
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anti-Sperm Associated Antigen 5 (SPAG5) (AA 1101-1193) antibody
SPAG5 适用: 大鼠 ELISA, IHC (fro), IHC (p), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Sperm Associated Antigen 5 (SPAG5) (AA 1-300) antibodySPAG5 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sperm Associated Antigen 5 (SPAG5) (AA 1082-1191) antibodySPAG5 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5F9 unconjugated
anti-Sperm Associated Antigen 5 (SPAG5) (N-Term) antibodySPAG5 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 说明
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HeLa cells were subjected to SDS PAGE followed by western blot with FNab08143(SPAG5 antibody) at dilution of 1:1000
- 限制
- 仅限研究用
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- 缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze / thaw cycles.
- 储存条件
- -20 °C
- 有效期
- 12 months
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- 抗原
- SPAG5 (Sperm Associated Antigen 5 (SPAG5))
- 别名
- SPAG5 (SPAG5 产品)
- 别名
- SPAG5 antibody, DEEPEST antibody, MAP126 antibody, hMAP126 antibody, AI874642 antibody, D11Bhm180e antibody, Deepest antibody, Mastrin antibody, S17 antibody, sperm associated antigen 5 antibody, sperm-associated antigen 5 antibody, SPAG5 antibody, LOC739263 antibody, Spag5 antibody
- 背景
- Synonyms: Background:Essential component of the mitotic spindle required for normal chromosome segregation and progression into anaphase(PubMed:11724960, PubMed:12356910). Required for chromosome alignment, normal timing of sister chromatid segregation, and maintenance of spindle pole architecture(PubMed:17664331). In complex with SKAP, promotes stable microtubule-kinetochore attachments. May contribute to the regulation of separase activity. May regulate AURKA localization to mitotic spindle, but not to centrosomes and CCNB1 localization to both mitotic spindle and centrosomes(PubMed:18361916, PubMed:21402792). Involved in centriole duplication. Required for CDK5RAP2, CEP152, WDR62 and CEP63 centrosomal localization and promotes the centrosomal localization of CDK2(PubMed:26297806). In non-mitotic cells, upon stress induction, inhibits mammalian target of rapamycin complex 1(mTORC1) association and recruits the mTORC1 component RPTOR to stress granules(SGs), thereby preventing mTORC1 hyperactivation-induced apoptosis(PubMed:23953116). May enhance GSK3B-mediated phosphorylation of other substrates, such as MAPT/TAU(PubMed:18055457).
- 基因ID
- 10615
- UniProt
- Q96R06
- 途径
- M Phase
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