GPR161 抗体
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- 抗原 See all GPR161 抗体
- GPR161 (G Protein-Coupled Receptor 161 (GPR161))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GPR161 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 免疫原
- G protein-coupled receptor 161
- 亚型
- IgG
- Top Product
- Discover our top product GPR161 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 说明
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HeLa cells were subjected to SDS PAGE followed by western blot with FNab03598(GPR161 antibody) at dilution of 1:500
- 限制
- 仅限研究用
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- 缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze / thaw cycles.
- 储存条件
- -20 °C
- 有效期
- 12 months
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- 抗原
- GPR161 (G Protein-Coupled Receptor 161 (GPR161))
- 别名
- GPR161 (GPR161 产品)
- 别名
- RE2 antibody, Gm208 antibody, Gm208Gpr antibody, vl antibody, RGD1563245 antibody, si:bz20i5.4 antibody, si:rp71-20i5.4 antibody, G protein-coupled receptor 161 antibody, GPR161 antibody, Gpr161 antibody, gpr161 antibody
- 背景
- Synonyms: Background:Key negative regulator of Shh signaling, which promotes the processing of GLI3 into GLI3R during neural tube development. Recruited by TULP3 and the IFT-A complex to primary cilia and acts as a regulator of the PKA-dependent basal repression machinery in Shh signaling by increasing cAMP levels, leading to promote the PKA-dependent processing of GLI3 into GLI3R and repress the Shh signaling. In presence of SHH, it is removed from primary cilia and is internalized into recycling endosomes, preventing its activity and allowing activation of the Shh signaling. Its ligand is unknown(By similarity).
- 分子量
- 70 kDa
- 基因ID
- 23432
- UniProt
- Q8N6U8
- 途径
- cAMP Metabolic Process
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