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KCNH1 抗体

KCNH1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5693254
发货至: 中国
  • 抗原 See all KCNH1 抗体
    KCNH1 (Potassium Voltage-Gated Channel, Subfamily H (Eag-Related), Member 1 (KCNH1))
    适用
    • 31
    • 26
    • 10
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 30
    • 1
    克隆类型
    • 31
    多克隆
    标记
    • 16
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This KCNH1 antibody is un-conjugated
    应用范围
    • 29
    • 15
    • 13
    • 13
    • 12
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB)
    品牌
    Picoband™
    序列
    AKRKSWARFK DACGKSEDWN KVSKAESMET LPERTKA
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for KCNH1 detection. Tested with WB in Human,Mouse,Rat.
    免疫原
    A synthetic peptide corresponding to a sequence of human KCNH1 (AKRKSWARFKDACGKSEDWNKVSKAESMETLPERTKA).
    Top Product
    Discover our top product KCNH1 Primary Antibody
  • 应用备注

    Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

    Application Details: Western blot, 0.1-0.5 μg/mL

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    缓冲液
    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
  • 抗原
    KCNH1 (Potassium Voltage-Gated Channel, Subfamily H (Eag-Related), Member 1 (KCNH1))
    别名
    KCNH1 (KCNH1 产品)
    别名
    EAG antibody, bEAG antibody, EAG1 antibody, Kv10.1 antibody, h-eag antibody, M-eag antibody, Eag1 antibody, kcnh1 antibody, potassium voltage-gated channel subfamily H member 1 antibody, potassium channel, voltage gated eag related subfamily H, member 1 antibody, potassium voltage-gated channel, subfamily H (eag-related), member 1 antibody, potassium voltage-gated channel, subfamily H (eag-related), member 1a antibody, KCNH1 antibody, LOC490277 antibody, Kcnh1 antibody, kcnh1a antibody
    背景

    Synonyms: Potassium voltage-gated channel subfamily H member 1, Ether-a-go-go potassium channel 1

    Tissue Specificity: Highly expressed in brain and in myoblasts at the onset of fusion, but not in other tissues. Detected in HeLa (cervical carcinoma), SH-SY5Y (neuroblastoma) and MCF-7 (epithelial tumor) cells, but not in normal epithelial cells.

    Background: Potassium voltage-gated channel subfamily H member 1 is a protein that in humans is encoded by the KCNH1 gene. Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit of a voltage-gated non-inactivating delayed rectifier potassium channel. It is activated at the onset of myoblast differentiation. The gene is highly expressed in brain and in myoblasts. Overexpression of the gene may confer a growth advantage to cancer cells and favor tumor cell proliferation. Alternative splicing of this gene results in two transcript variants encoding distinct isoforms.

    UniProt
    O95259
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