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CASR 抗体 (AA 926-1078)

This anti-CASR antibody is a 小鼠单克隆 antibody detecting CASR in WB. Suitable for 人.

产品编号 ABIN5693096

发货至: 中国

Quick Overview for CASR 抗体 (AA 926-1078) (ABIN5693096)

抗原

See all CASR 抗体

CASR (Calcium-Sensing Receptor (CASR))

适用

91
50
39
7
4
4
4
2
2
2
2
2
1

人

宿主

小鼠

克隆类型

单克隆

标记

45
8
7
5
3
3
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1

This CASR antibody is un-conjugated

应用范围

79
36
23
22
17
9
7
7
5
2
2
2
1

Western Blotting (WB)

克隆位点

11E9

Discover our top product CASR Primary Antibody

抗原表位
21

15

14

8

6

4

4

3

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1
AA 926-1078

原理

Anti-CASR Antibody Picoband® (monoclonal, 11E9)

交叉反应（详细）

No cross-reactivity with other proteins.

产品特性

Anti-CASR Antibody Picoband® (monoclonal, 11E9) (ABIN5693096). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

免疫原

E. coli-derived human CASR recombinant protein (Position: Q926-S1078). Human CASR shares 80.5% and 78.6% amino acid (aa) sequence identity with mouse and rat CASR, respectively.

亚型

IgG2b
anti-Calcium-Sensing Receptor (CASR) (AA 874-1088) antibody
CASR 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Calcium-Sensing Receptor (CASR) (pThr888) antibody
CASR 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Calcium-Sensing Receptor (CASR) (AA 121-220) antibody
CASR 适用: Pig WB, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Calcium-Sensing Receptor (CASR) (C-Term) antibody
CASR 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Calcium-Sensing Receptor (CASR) antibody
CASR 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Calcium-Sensing Receptor (CASR) (AA 926-1078) antibody
CASR 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Calcium-Sensing Receptor (CASR) (AA 216-229), (Extracellular) antibody
CASR 适用: 人 WB, IHC, IF, FACS, LCI, IC 宿主: 兔 Polyclonal unconjugated

anti-Calcium-Sensing Receptor (CASR) (AA 863-1079) antibody
CASR 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated

anti-Calcium-Sensing Receptor (CASR) antibody
CASR 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Calcium-Sensing Receptor (CASR) (AA 260-287) antibody
CASR 适用: 小鼠 WB 宿主: 兔 Polyclonal RB41198 unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL
1. Coburn JW, Elangovan L, Goodman WG, Fraza111 JM (Dec 1999). "Calcium-sensing receptor and calcimimetic agents". Kidney International. Supplement 73: S52-8. 2. D'Souza-Li L (Aug 2006). "The calcium-sensing receptor and related diseases". Arquivos Brasileiros De Endocrinologia E Metabologia 50 (4): 628-39. 3. Pidasheva S, Canaff L, Simonds WF, Marx SJ, Hendy GN (Jun 2005). "Impaired cotranslational processing of the calcium-sensing receptor due to signal peptide missense mutations in familial hypocalciuric hypercalcemia". Human Molecular Genetics 14 (12): 1679-90.

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
抗原

CASR (Calcium-Sensing Receptor (CASR))

别名

CASR

背景

Synonyms: Extracellular calcium-sensing receptor, CaR
Tissue Specificity: Expressed in the temporal lobe, frontal lobe, parietal lobe, hippocampus, and cerebellum. Also found in kidney, lung, liver, heart, skeletal muscle, placenta.
Background: The calcium-sensing receptor (CaSR) is a G protein-coupled receptor that is expressed in the parathyroid hormone (PTH)-producing chief cells of the parathyroid gland, and the cells lining the kidney tubule. It senses small changes in circulating calcium concentration and couples this information to intracellular signaling pathways that modify PTH secretion or renal cation handling, thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene cause familial hypocalciuric hypercalcemia, familial, isolated hypoparathyroidism, and neonatal severe primary hyperparathyroidism.

分子量

130 kDa

基因ID

846

UniProt

P41180

途径

Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis

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