APEX1 抗体 (AA 2-318)
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- 抗原 See all APEX1 抗体
- APEX1 (Apurinic/Apyrimidinic Endonuclease 1 (APEX1))
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抗原表位
- AA 2-318
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This APEX1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 品牌
- Picoband™
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
- Mouse IgG monoclonal antibody for APE1 detection. Tested with WB, IHC-P, IHC-F, ICC, FCM in Human.
- 免疫原
- E.coli-derived human APE1 recombinant protein (Position: P2-L318). Human APE1 shares 94% and 93% amino acid (aa) sequence identity with mouse and rat APE1, respectively.
- 克隆位点
- 5C11
- 亚型
- IgG2b
- Top Product
- Discover our top product APEX1 Primary Antibody
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anti-Apurinic/Apyrimidinic Endonuclease 1 (APEX1) (AA 1-318) antibody
APEX1 适用: 人 WB, IF, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-Apurinic/Apyrimidinic Endonuclease 1 (APEX1) (AA 1-242) antibodyAPEX1 适用: 人, 犬, 猴 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 1H9 unconjugated
anti-Apurinic/Apyrimidinic Endonuclease 1 (APEX1) (AA 219-318) antibodyAPEX1 适用: 人, 大鼠, 猴 WB, ELISA, IHC, ICC, FACS, Neut 宿主: 小鼠 Monoclonal 7A2G7 unconjugated
anti-Apurinic/Apyrimidinic Endonuclease 1 (APEX1) (AA 1-318) antibodyAPEX1 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Apurinic/Apyrimidinic Endonuclease 1 (APEX1) (AA 2-318) antibodyAPEX1 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Apurinic/Apyrimidinic Endonuclease 1 (APEX1) antibodyAPEX1 适用: 人 WB, IF, IHC (p) 宿主: 小鼠 Monoclonal 1518CT337-123-86-269-232 unconjugated
anti-Apurinic/Apyrimidinic Endonuclease 1 (APEX1) (acLys6) antibodyAPEX1 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Apurinic/Apyrimidinic Endonuclease 1 (APEX1) (N-Term) antibodyAPEX1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Apurinic/Apyrimidinic Endonuclease 1 (APEX1) (AA 1-318) antibodyAPEX1 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Apurinic/Apyrimidinic Endonuclease 1 (APEX1) antibodyAPEX1 适用: 人, 小鼠, 大鼠, 兔 WB, IHC, IF, ICC, ChIP, IP, Neut 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P), IHC(F) and ICC.
Application Details: Western blot, 0.1-0.5 μg/mL
Immunohistochemistry(Paraffin-embedded Section), 0.5-1 μg/mL
Immunohistochemistry(Frozen Section), 0.5-1 μg/mL
Immunocytochemistry, 0.5-1 μg/mL
Flow Cytometry, 1-3 μg/1x106 cells - 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
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- 抗原
- APEX1 (Apurinic/Apyrimidinic Endonuclease 1 (APEX1))
- 别名
- APEX1 (APEX1 产品)
- 别名
- apex1 antibody, MGC76280 antibody, MGC79645 antibody, MGC78928 antibody, APE antibody, APE1 antibody, APEN antibody, APEX antibody, APX antibody, HAP1 antibody, REF1 antibody, Apex antibody, REF-1 antibody, BAP1 antibody, apex1a antibody, hm:zehn1532 antibody, wu:fc13d11 antibody, zgc:66204 antibody, Ref-1 antibody, apurinic/apyrimidinic endodeoxyribonuclease 1 antibody, APEX nuclease (multifunctional DNA repair enzyme) 1 antibody, APEX nuclease (multifunctional DNA repair enzyme) 1 L homeolog antibody, DNA-(apurinic or apyrimidinic site) lyase antibody, apurinic/apyrimidinic endonuclease 1 antibody, APEX1 antibody, apex1 antibody, apex1.L antibody, CNG03640 antibody, CNH01280 antibody, nth antibody, Spirs_4119 antibody, Palpr_0103 antibody, Apex1 antibody
- 背景
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Synonyms: DNA-(apurinic or apyrimidinic site) lyase, APEX nuclease, APEN, Apurinic-apyrimidinic endonuclease 1, AP endonuclease 1, APE-1, REF-1, Redox factor-1, DNA-(apurinic or apyrimidinic site) lyase, mitochondrial, APEX1, APE, APE1, APEX, APX, HAP1, REF1
Background: APEX1, also called apurinic endonuclease (APE), is a DNA repair enzyme having apurinic/apyrimidinic (AP) endonuclease, 3-prime, 5-prime-exonuclease, DNA 3-prime repair diesterase, and DNA 3-prime-phosphatase activities. The human APEX1 gene consists of 5 exons spanning 2.64 kb and exists as a single copy in the haploid genome. Using in situ hybridization, the APEX1 gene is mapped to 14q11.2-q12. The predicted APEX1 protein, which contained probable nuclear transport signals, was identified as a member of a family of DNA repair enzymes found in lower organisms. The abundance of the large form of APEX1 was increased in leiomyoma extracts relative to myometrial tissue extracts, and the large form was dominant in cell lines derived from leiomyosarcomas. The exonuclease activity of nuclear APEX1 can remove the anti-HIV nucleoside analogs AZT and D4T from the 3-prime terminus of a nick more efficiently than can cytosolic exonucleases.
- UniProt
- P27695
- 途径
- DNA Damage Repair, Chromatin Binding, Cell RedoxHomeostasis, Smooth Muscle Cell Migration, Positive Regulation of Response to DNA Damage Stimulus
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