TBP 抗体 (AA 38-107)
Quick Overview for TBP 抗体 (AA 38-107) (ABIN5692949)
抗原
See all TBP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
 - AA 38-107
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原理
 - Anti-TATA binding protein TBP Antibody Picoband®
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交叉反应 (详细)
 - No cross-reactivity with other proteins.
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产品特性
 - Anti-TATA binding protein TBP Antibody Picoband® (ABIN5692949). Tested in ELISA, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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免疫原
 - E. coli-derived mouse Tbp recombinant protein (Position: L38-A107).
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亚型
 - IgG
 
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应用备注
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                        Western blot, 0.1-0.5 μg/mL
ELISA, 0.1-0.5 μg/mL
1. Bauer, P., Laccone, F., Rolfs, A., Wullner, U., Bosch, S., Peters, H., Liebscher, S., Scheible, M., Epplen, J. T., Weber, B. H. F., Holinski-Feder, E., Weirich-Schwaiger, H., Morris-Rosendahl, D. J., Andrich, J., Riess, O.Trinucleotide repeat expansion in SCA17/TBP in white patients with Huntington's disease-like phenotype.J. Med. Genet. 41: 230-232, 2004. 2. Stevanin, G., Fujigasaki, H., Lebre, A.-S., Camuzat, A., Jeannequin, C., Dode, C., Takahashi, J., San, C., Bellance, R., Brice, A., Durr, A.Huntington's disease-like phenotype due to trinucleotide repeat expansions in the TBP and JPH3 genes.Brain 126: 1599-1603, 2003. 3. Veenstra, G. J. C., Weeks, D. L., Wolffe, A. P.Distinct roles for TBP and TBP-like factor in early embryonic gene transcription in Xenopus.Science 290: 2312-2314, 2000. - 
                                            
限制
 - 仅限研究用
 
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状态
 - Lyophilized
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溶解方式
 - Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
 - 500 μg/mL
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缓冲液
 - Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
 - Sodium azide
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注意事项
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
 - 4 °C,-20 °C
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储存方法
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                        Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. 
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. 
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- TBP (TATA Box Binding Protein (TBP))
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别名
 - Tbp
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背景
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Synonyms: TATA-box-binding protein, TATA sequence-binding protein, TATA-binding factor, TATA-box factor, Transcription initiation factor TFIID TBP subunit, Tbp, Tfiid
Tissue Specificity: Ubiquitously expressed.
Background: TBP, TATA-binding protein, is a general transcription factor that binds specifically to a DNA sequence called the TATA box. The TBP gene is mapped to 6q27. This DNA sequence is found about 35 base pairs upstream of the transcription start site in some eukaryotic gene promoters. TBP, along with a variety of TBP-associated factors, make up the TFIID, a general transcription factor that in turn makes up part of the RNA polymerase II preinitiation complex. As one of the few proteins in the preinitiation complex that binds DNA in a sequence-specific manner, it helps position RNA polymerase II over the transcription start site of the gene. However, it is estimated that only 10-20 % of human promoters have TATA boxes. Therefore, TBP is probably not the only protein involved in positioning RNA polymerase II.
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分子量
 - 38 kDa
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基因ID
 - 21374
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UniProt
 - P29037
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途径
 - WNT signaling
 
抗原
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