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- 抗原 See all CRTC2 抗体
- CRTC2 (CREB Regulated Transcription Coactivator 2 (CRTC2))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CRTC2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 品牌
- Picoband™
- 序列
- EKIALQKQRQ AEETAAFEEV MMDIGSTRLQ AQKLRLAYTR
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
- Rabbit IgG polyclonal antibody for TORC2 detection. Tested with WB in Human,Mouse,Rat.
- 免疫原
- A synthetic peptide corresponding to a sequence of human TORC2 (EKIALQKQRQAEETAAFEEVMMDIGSTRLQAQKLRLAYTR).
- Top Product
- Discover our top product CRTC2 Primary Antibody
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anti-CREB Regulated Transcription Coactivator 2 (CRTC2) (C-Term) antibody
Verified CRTC2 适用: 人, 大鼠 WB, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-CREB Regulated Transcription Coactivator 2 (CRTC2) antibodyCRTC2 适用: 人, 猴 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 5B10 unconjugated
anti-CREB Regulated Transcription Coactivator 2 (CRTC2) (pSer171) antibodyCRTC2 适用: 人, 小鼠 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-CREB Regulated Transcription Coactivator 2 (CRTC2) (AA 595-693) antibodyCRTC2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E6 unconjugated
anti-CREB Regulated Transcription Coactivator 2 (CRTC2) (AA 180-372) antibodyCRTC2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-CREB Regulated Transcription Coactivator 2 (CRTC2) (AA 83-96) antibodyVerified CRTC2 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-CREB Regulated Transcription Coactivator 2 (CRTC2) (AA 595-693) antibodyCRTC2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-CREB Regulated Transcription Coactivator 2 (CRTC2) (AA 542-553) antibodyVerified CRTC2 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
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- 应用备注
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Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.
Application Details: Western blot, 0.1-0.5 μg/mL
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
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- 抗原
- CRTC2 (CREB Regulated Transcription Coactivator 2 (CRTC2))
- 别名
- CRTC2 (CRTC2 产品)
- 别名
- CRTC2 antibody, TORC-2 antibody, TORC2 antibody, 4632407F12Rik antibody, Torc2 antibody, mTORC2 antibody, RGD1308903 antibody, CREB regulated transcription coactivator 2 antibody, CRTC2 antibody, Crtc2 antibody
- 背景
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Synonyms: CREB-regulated transcription coactivator 2, Transducer of regulated cAMP response element-binding protein 2, TORC-2, Transducer of CREB protein 2, CRTC2, TORC2
Tissue Specificity: Most abundantly expressed in the thymus. Present in both B and T-lymphocytes. Highly expressed in HEK293T cells and in insulinomas. High levels also in spleen, ovary, muscle and lung, with highest levels in muscle. Lower levels found in brain, colon, heart, kidney, prostate, small intestine and stomach. Weak expression in liver and pancreas.
Background: CREB regulated transcription coactivator 2, also known as CRTC2, is a protein which in humans is encoded by the CRTC2 gene. This gene encodes a member of the transducers of regulated cAMP response element-binding protein activity family of transcription coactivators. These proteins promote the transcription of genes targeted by the cAMP response element-binding protein, and therefore play an important role in many cellular processes. Under basal conditions the encoded protein is phosphorylated by AMP-activated protein kinase or the salt-inducible kinases and is sequestered in the cytoplasm. Upon activation by elevated cAMP or calcium, the encoded protein translocates to the nucleus and increases target gene expression. Single nucleotide polymorphisms in this gene may increase the risk of type 2 diabetes. A pseudogene of this gene is located on the long arm of chromosome 5.
- 途径
- AMPK Signaling, Carbohydrate Homeostasis
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