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Vinculin 抗体

VCL 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5690320
发货至: 中国
  • 抗原 See all Vinculin (VCL) 抗体
    Vinculin (VCL)
    适用
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    人, 小鼠, 大鼠
    宿主
    • 93
    • 27
    • 1
    克隆类型
    • 84
    • 37
    多克隆
    标记
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    This Vinculin antibody is un-conjugated
    应用范围
    • 86
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    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    Vinculin antibody is human, mouse and rat reactive. At least three isoforms of Vinculin are known to exist.
    纯化方法
    Vinculin antibody is affinity chromatography purified via peptide column.
    免疫原
    Vinculin antibody was raised against a 23 amino acid peptide near the amino of human Vinculin.
    亚型
    IgG
    Top Product
    Discover our top product VCL Primary Antibody
  • 应用备注
    Vinculin antibody can be used for detection of Vinculin by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Vinculin antibody is supplied in PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Vinculin antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • 抗原
    Vinculin (VCL)
    别名
    Vinculin (VCL 产品)
    别名
    CMD1W antibody, CMH15 antibody, MV antibody, MVCL antibody, VCL antibody, im:6902790 antibody, hm:zehn2160 antibody, DDBDRAFT_0186762 antibody, DDBDRAFT_0232320 antibody, DDB_0186762 antibody, DDB_0232320 antibody, 9430097D22 antibody, AA571387 antibody, AI462105 antibody, AW545629 antibody, CG3299 antibody, CT11081 antibody, Dmel\\CG3299 antibody, Dmvincp antibody, EG:103B4.1 antibody, Vin antibody, Vin2EF antibody, vinc antibody, LOC100228062 antibody, vcl-A antibody, vinculin antibody, vinculin a antibody, vinculin A antibody, Vinculin antibody, vinculin S homeolog antibody, VCL antibody, vcla antibody, vinA antibody, Vcl antibody, Vinc antibody, CpipJ_CPIJ013873 antibody, Bm1_37935 antibody, vcl antibody, vcl.S antibody
    背景
    Vinculin is a cytoskeletal protein that plays an important role in the regulation of focal adhesions and embryonic development (1). Three structural vinculin domains include an amino-terminal head, a short flexible proline-rich region and a carboxy-terminal tail (2). Expression of vinculin were shown to be affected by the level of actin expression (2,3). Vinculin deficiencies are associated with a decrease in cell adhesion and an increase in cell motility, suggesting a possible role in metastatic growth (4). Defects in VCL are the cause of cardiomyopathy dilated type 1W (CMD1W) (5).
    分子量
    Predicted: 120 kDa

    Observed: 117 kDa
    基因ID
    7414
    NCBI登录号
    NP_003364
    途径
    Cell-Cell Junction Organization, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2
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