BCL2L1 抗体 (AA 60-64)
Quick Overview for BCL2L1 抗体 (AA 60-64) (ABIN5689429)
抗原
See all BCL2L1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 60-64
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特异性
- This antibody detects endogenous level of total BCL-XL protein.
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纯化方法
- Antibodies were purified by affinity-chromatography using epitope-specific peptide.
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免疫原
- BCL-XL (Ab-62) antibody was raised against a peptide sequence around aa.60~64 (A-D-S-P-A) derived from human BCL-XL .
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应用备注
- Western Blot: 1:500~1:1000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store antibody at -20°C for up to one year.
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- BCL2L1 (BCL2-Like 1 (BCL2L1))
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别名
- BCL XL
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背景
- Potent inhibitor of cell death. Isoform Bcl-X(L) anti-apoptotic activity is inhibited by association with SIVA isoform 1. Inhibits activation of caspases By similarity. Appears to regulate cell death by blocking the voltage-dependent anion channnel (VDAC) by binding to it and preventing the release of the caspase activator, cytochrome c, from the mitochondrial membrane. The Bcl-X(S) isoform promotes apoptosis.
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分子量
- 30 kDa
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基因ID
- 598
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NCBI登录号
- NP_612815
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UniProt
- Q07817
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途径
- Apoptosis, Negative Regulation of intrinsic apoptotic Signaling
抗原
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